置管后开始腹膜透析时间对老年终末期肾病患者生存率、肾脏功能及并发症的影响

发布时间：2018-08-06 09:58

【摘要】：目的探讨置管后开始腹膜透析时间对老年终末期肾病(ESRD)患者生存率、肾脏功能及并发症的影响。方法接受腹膜透析ESRD患者106例依置管后开始透析时间分为两组,早期组36例置管后1~5 d开始透析,晚期组70例置管后1~2 w开始透析,均随访2年,观察两组肾功能指标变化,随访期间并发症发生情况、死亡情况及生存质量。结果两组治疗前肾功能指标差异无统计学意义(P0.05)。早期组治疗后5、30 d肾功能指标均低于同组治疗前及晚期组(P0.05)。两组治疗前生活质量评定量表(SF-36)各项指标差异无统计学意义(P0.05),早期组治疗后1、3个月各项指标评分均高于同组治疗前及晚期组同期(P0.05)。随访2年,早期组新增心血管、脑血管、感染、出血并发症发生率及死亡率均低于晚期组(P0.05)。结论老年ESRD患者置管后早期进行腹膜透析,可延长生存期、降低置管后并发症、提高生存质量。
[Abstract]:Objective to investigate the effect of peritoneal dialysis time after catheter placement on survival rate, renal function and complications in elderly patients with end stage renal disease (ESRD). Methods 106 patients with ESRD undergoing peritoneal dialysis were divided into two groups according to the time of dialysis. 36 patients in the early group began dialysis at 1 and 5 days after catheterization, and 70 patients in the late group began dialysis at 1 and 2 weeks after catheterization. All patients were followed up for 2 years to observe the changes of renal function in both groups. Complications, mortality and quality of life were observed during follow-up. Results there was no significant difference in renal function between the two groups before treatment (P0.05). The indexes of renal function in the early group were lower than those in the same group before and after treatment (P0.05). The quality of life rating scale (SF-36) had no significant difference between the two groups before treatment (P0.05). The scores of each index in the early group were higher than those in the same group before and after treatment (P0.05). 3 months after treatment, the scores of each index in the early group were higher than those in the same group (P0.05). After 2 years follow-up, the incidence of cardiovascular, cerebrovascular, infection, bleeding complications and mortality in the early group were lower than those in the late group (P0.05). Conclusion Peritoneal dialysis can prolong survival, reduce complications and improve quality of life in elderly patients with ESRD.
【作者单位】：天津医科大学第二医院;
【分类号】：R692.5

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