上尿路结石梗阻合并高血压患者解除梗阻后血压变化及其影响因素分析
发布时间:2018-08-13 20:14
【摘要】:目的:探讨上尿路结石梗阻合并高血压患者解除梗阻后血压动态变化及其影响因素,为临床治疗提供一定的理论和指导依据。方法:以2014年7月至2016年12月在遵义医学院附属医院行手术治疗的110例上尿路结石梗阻合并高血压患者为研究对象,收集研究对象术前到术后1月的血压情况。单因素比较患者性别、年龄、结石类型、手术方式、梗阻时间、肾脏积水程度、结石分布、结石大小、高血压分级、肾素(PRA)及血管紧张素Ⅱ(AngⅡ)值等对上尿路结石致高血压患者术后血压恢复率的影响差异(χ2检验,P0.05),筛选出单因素分析有统计学意义的变量用Logistic回归分析法进行多因素分析影响上尿路结石梗阻合并高血压患者术后血压恢复的危险因素。分别比较不同梗阻时间、肾脏积水程度、PRA及AngⅡ值患者术后收缩压和舒张压下降程度(t检验,P0.05)。结果:在单因素分析统计分析中,不同结石梗阻时间、肾脏积水程度、PRA及AngⅡ值正常与否各组患者术后1月血压恢复率差异有统计学意义(P0.05);患者性别、年龄、结石类型、手术方式、结石大小、结石分布、高血压分级与术后血压是否下降无统计学相关性(P0.05)。梗阻时间大于3个月的患者术后血压恢复率及血压下降程度均低于梗阻时间小于3个月的患者,差异均有统计学意义(P0.05);中重度肾脏积水患者术后血压恢复率及血压下降程度均低于轻度肾积水患者,差异均有统计学意义(P0.05);PRA及AngⅡ值升高的患者术后血压恢复率及血压下降程度均低于PRA及AngⅡ值正常的患者,差异均有统计学意义(P0.05)。Logistic回归多因素分析得出梗阻时间(OR=1.841)、肾脏积水程度(OR=2.997)、PRA及AngⅡ值(OR=3.931)是解除梗阻后高血压持续的的危险因素。结论:上尿路结石梗阻合并高血压患者在解除梗阻后血压可不同程度的恢复。梗阻时间3个月、肾脏中重度积水、PRA及AngⅡ值升高组患者术后收缩压及舒张压下降程度分别小于梗阻时间≤3个月、肾脏轻度积水、PRA及AngⅡ值正常患者。结石梗阻时间长、肾脏积水程度重及AngⅡ及PRA值升高是上尿路结石梗阻合并高血压患者解除梗阻后高血压持续的危险因素。
[Abstract]:Objective: to investigate the dynamic changes of blood pressure and its influencing factors in patients with upper urinary stone obstruction and hypertension, and to provide some theoretical and guiding basis for clinical treatment. Methods: from July 2014 to December 2016, 110 patients with upper urinary tract obstruction complicated with hypertension were treated in the affiliated Hospital of Zunyi Medical College. Sex, age, type of stone, operative method, time of obstruction, degree of hydronephrosis, distribution of stone, stone size, grade of hypertension, The effect of renin (PRA) and angiotensin 鈪,
本文编号:2182059
[Abstract]:Objective: to investigate the dynamic changes of blood pressure and its influencing factors in patients with upper urinary stone obstruction and hypertension, and to provide some theoretical and guiding basis for clinical treatment. Methods: from July 2014 to December 2016, 110 patients with upper urinary tract obstruction complicated with hypertension were treated in the affiliated Hospital of Zunyi Medical College. Sex, age, type of stone, operative method, time of obstruction, degree of hydronephrosis, distribution of stone, stone size, grade of hypertension, The effect of renin (PRA) and angiotensin 鈪,
本文编号:2182059
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