妇科患者泌尿系感染病原菌分布及血清炎症因子水平的变化研究

发布时间：2018-08-21 19:35

【摘要】：目的探讨妇科患者泌尿系感染病原菌分布及血清炎症因子水平的变化,为妇科泌尿系感染患者的临床诊治提供参考。方法选取2016年1-8月在医院诊治的100例妇科泌尿系感染患者(研究组)与50例单纯妇科生殖道感染患者(对照组),检测降钙素原(PCT)、白细胞介素-2(IL-2)、白细胞介素-6(IL-6)、白细胞介素-8(IL-8)、肿瘤坏死因子-α(TNF-α),对研究组患者中段尿进行细菌培养及菌株鉴定。结果研究组患者中4例为多重病原菌感染,17例为双重病原菌感染,79例为单纯病原菌感染,分别占4.00%、17.00%、79.00%,共培养出病原菌125株,其中革兰阴性菌71株、革兰阳性菌25株、真菌4株、衣原体7株、支原体18株,分别占56.80%、20.00%、3.20%、5.60%、14.40%;研究组患者PCT、IL-2、IL-6、IL-8、TNF-α水平高于对照组(P0.05)。结论妇科泌尿系感染患者主要表现为大肠埃希菌、支原体、粪肠球菌为主的单纯感染,可引起血清炎性因子进一步升高,同时支原体与衣原体检测应作为常规检测项目。
[Abstract]:Objective to investigate the distribution of pathogenic bacteria and the level of serum inflammatory factors in gynecological patients with urinary tract infection, and to provide reference for clinical diagnosis and treatment of gynecological urinary tract infection. Methods from January to August 2016, 100 patients with gynecologic urinary tract infection (study group) and 50 patients with gynecological genital tract infection (control group) were selected to detect procalcitonin (PCT), interleukin-2 (IL-2), interleukin-6 (IL-6) and fine white. Interleukin-8 (IL-8) and tumor necrosis factor- 伪 (TNF- 伪) were used to culture the bacteria and identify the strains of the patients in the study group. Results in the study group, there were 4 cases of multiple pathogenic bacteria infection and 17 cases of double pathogenic bacteria infection. 79 cases were pure pathogen infection, accounting for 4.00 ~ 17.00% and 79.00% respectively. 125 strains of pathogens were cultured, including 71 Gram-negative bacteria, 25 Gram-positive bacteria and 4 fungi. There were 7 strains of chlamydia and 18 strains of mycoplasma, accounting for 56.80% 20.00% and 5.60% and 14.40%, respectively, and the levels of PCTIL-2IL-6 IL-6 IL-8 TNF- 伪 in the study group were higher than those in the control group (P0.05). Conclusion the infection of Escherichia coli, mycoplasma and Enterococcus faecalis in gynecological patients with urinary tract infection can cause the further increase of serum inflammatory factors, and the detection of mycoplasma and chlamydia should be regarded as a routine detection item.
【作者单位】：温州市计划生育宣传技术指导站妇产科;温州市人民医院妇产科;
【基金】：浙江省科技计划基金资助项目(Y20140564)
【分类号】：R691.3

【相似文献】