前列腺组织学炎症程度及血清hs-CRP水平与BPH患者总前列腺体积、国际前列腺症状评分的关系
发布时间：2018-08-27 12:15
【摘要】：目的观察前列腺组织学炎症程度及血清高敏C反应蛋白(hs-CRP)水平与良性前列腺增生(BPH)患者总前列腺体积(TPV)、国际前列腺症状评分(IPSS)的关系。方法 BPH患者302例,按照是否合并前列腺组织学炎症将患者分为不伴组织学炎症组(195例)和伴组织学炎症组(107例),并按照血清hs-CRP是否正常分为hsCRP正常组(213例)和hs-CRP升高组(89例),比较不伴组织学炎症组与伴组织学炎症组IPSS、TPV、前列腺特异性抗原(PSA)、PSA密度(PSAD),比较hs-CRP正常组与hs-CRP升高组IPSS、TPV、PSA、PSAD。使用Spearman等级相关性分析前列腺组织学炎症程度及血清hs-CRP水平与IPSS、TPV、PSA、PSAD的关系。结果伴组织学炎症组、不伴组织学炎症组TPV分别为56.22(36.76~79.03)、43.04(30.32~66.09)m L,IPSS分别为19.0(12.0~24.0)、15.0(7.0~22.0)分,PSA分别为10.60(7.79~18.86)、10.07(5.20~16.59)ng/m L,PSAD分别为0.20(0.12~0.35)、0.19(0.11~0.40)ng/(m L·cm3),两组IPSS、TPV比较,P均0.05。前列腺组织学炎症程度与IPSS、TPV呈正相关(r分别为0.14、0.18,P均0.05)。hs-CRP升高组、hs-CRP正常组TPV分别为45.86(33.95~66.92)、45.73(30.55~71.95)m L,IPSS分别为18.0(10.5~26.0)、16.0(7.0~22.0)分,PSA分别为11.93(6.23~22.98)、9.87(6.17~15.21)ng/m L,PSAD分别为0.23(0.10~0.51)、0.19(0.12~0.32)ng/(m L·cm3),两组IPSS、PSA比较,P均0.05。血清hs-CRP与IPSS、PSA呈正相关(r分别为0.19、0.12,P0.05或0.01)。结论前列腺组织学炎症程度与BPH患者IPSS、TPV有关,血清hs-CRP水平与IPSS、PSA有关。
[Abstract]:Objective to investigate the relationship between the degree of histologic inflammation of prostate and the serum level of Gao Min C-reactive protein (hs-CRP) in patients with benign prostatic hyperplasia (BPH) and the total prostate volume (TPV), international prostate symptom score (IPSS) in patients with benign prostatic hyperplasia (BPH). Methods 302 BPH patients, The patients were divided into two groups according to whether they were complicated with histologic inflammation of prostate (195 cases) and with histologic inflammation (107 cases). According to whether the serum hs-CRP was normal or not, the patients were divided into normal hsCRP group (213 cases) and elevated hs-CRP group (89 cases). Comparison of IPSS,TPV, prostate specific antigen (PSA) density (PSAD), between non-histologic inflammation group and histologic inflammation group IPSS,TPV,PSA,PSAD. in normal hs-CRP group and hs-CRP elevated group Spearman grade correlation was used to analyze the relationship between the degree of prostatic histologic inflammation and the level of serum hs-CRP and IPSS,TPV,PSA,PSAD. Results in the group with histologic inflammation, the TPV of the group without histologic inflammation was 56.22 (36.7679.03) 43.04 (30.320.66.09) mLPSS was 19.0 (12.00.24.0) and 15.0 (7.00.22.0), respectively. The TPV of the group without histologic inflammation was 10.07 (7.7918.86) 10.07 (5.201.59) ng/m LPSAD was 0.20 (0.120.35) and 0.19 (0.110.40) ng/ (m L cm3, respectively (P < 0.05). 鍓嶅垪鑵虹粍缁囧鐐庣棁绋嬪害涓嶪PSS,TPV鍛堟鐩稿叧(r鍒嗗埆涓，
本文编号：2207247
[Abstract]:Objective to investigate the relationship between the degree of histologic inflammation of prostate and the serum level of Gao Min C-reactive protein (hs-CRP) in patients with benign prostatic hyperplasia (BPH) and the total prostate volume (TPV), international prostate symptom score (IPSS) in patients with benign prostatic hyperplasia (BPH). Methods 302 BPH patients, The patients were divided into two groups according to whether they were complicated with histologic inflammation of prostate (195 cases) and with histologic inflammation (107 cases). According to whether the serum hs-CRP was normal or not, the patients were divided into normal hsCRP group (213 cases) and elevated hs-CRP group (89 cases). Comparison of IPSS,TPV, prostate specific antigen (PSA) density (PSAD), between non-histologic inflammation group and histologic inflammation group IPSS,TPV,PSA,PSAD. in normal hs-CRP group and hs-CRP elevated group Spearman grade correlation was used to analyze the relationship between the degree of prostatic histologic inflammation and the level of serum hs-CRP and IPSS,TPV,PSA,PSAD. Results in the group with histologic inflammation, the TPV of the group without histologic inflammation was 56.22 (36.7679.03) 43.04 (30.320.66.09) mLPSS was 19.0 (12.00.24.0) and 15.0 (7.00.22.0), respectively. The TPV of the group without histologic inflammation was 10.07 (7.7918.86) 10.07 (5.201.59) ng/m LPSAD was 0.20 (0.120.35) and 0.19 (0.110.40) ng/ (m L cm3, respectively (P < 0.05). 鍓嶅垪鑵虹粍缁囧鐐庣棁绋嬪害涓嶪PSS,TPV鍛堟鐩稿叧(r鍒嗗埆涓，
本文编号：2207247
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