器官捐献肾移植功能延迟恢复的预后因素分析

发布时间：2018-08-30 12:17

【摘要】：目的探讨中国公民逝世后器官捐献(Chinese donation after citizens’death,CDCD)发生肾移植功能延迟恢复(delayed graft function,DGF)的预后因素。方法回顾性分析2014年1月~2015年11月在武汉大学中南医院138例行同种异体肾移植手术的临床资料,21例发生DGF(DGF组),117例移植肾功能稳定(immediate graft function,IGF)为IFG组,采用χ~2检验进行单因素分析,再用logistic模型对有统计学差异的因素进行多因素分析。结果 DGF发生率为15.2%(21/138),单因素分析显示DGF的预后因素包括受者术前血透时间≥12个月(P=0.024)、脑出血死亡供者(P=0.020)、供者血清肌酐≥177μmol/L(P=0.013)、热缺血时间≥15 min(P=0.041)、冷缺血时间≥12 h(P=0.025)及供者经历心肺复苏(P=0.001)有显著性差异。logistic多因素分析显示供者血清肌酐≥177μmol/L(OR=7.138,95%CI:1.418~35.937,P=0.017)、供者心肺复苏(OR=30.207,95%CI:3.653~111.778,P=0.001)及热缺血时间≥15 min(OR=7.762,95%CI:1.953~30.845,P=0.004)是DGF的独立预后因素。结论供者血清肌酐≥177μmol/L、供者经历心肺复苏及热缺血时间≥15 min是导致CDCD发生DGF的预后因素。
[Abstract]:Objective to investigate the prognostic factors of delayed recovery of renal transplantation (delayed graft function,DGF) in (Chinese donation after citizens'death,CDCD after death of Chinese citizens. Methods from January 2014 to November 2015, we retrospectively analyzed the clinical data of 138 cases of allograft renal transplantation performed in Central South Hospital of Wuhan University (21 cases of DGF (DGF group) and 117 cases of stable renal function (immediate graft function,IGF) as IFG group. Univariate analysis was performed by 蠂 ~ 2 test. Logistic model was used to analyze the factors with statistical difference. Results the incidence of DGF was 15.2% (21 / 138). Univariate analysis showed that the prognostic factors of DGF included preoperative hemodialysis time 鈮，

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