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经尿道半导体激光前列腺剜除术与前列腺电切术治疗不同体积良性前列腺增生的临床对比分析

发布时间:2018-09-07 12:50
【摘要】:目的:对比分析经尿道半导体激光前列腺剜除术(DIOD)与前列腺电切术(TURP)治疗不同体积良性前列腺增生(BPH)的临床疗效。方法:回顾性分析2012年3月至2015年8月本院收治的256例BPH患者,其中141例采用DIOD,115例采用TURP。术前按前列腺体积大小分为3组,60 ml组中42例行DIOD术,31例行TURP术;60~80 ml组中51例行DIOD术,45例行TURP术;80 ml组中48例行DIOD术,39例行TURP术;对比分析3组患者两种治疗方法的临床疗效,各组围手术期平均手术时间、血红蛋白变化率、Na+变化率、膀胱冲洗时间、留置尿管时间,以及术前术后血清PSA、IPSS评分、最大尿流率(Qmax)、残余尿(PVR)等指标变化。结果:60 ml组围手术期各项指标及术后随访指标在两种手术方法间无明显差异;60~80 ml组中DIOD组血红蛋白变化[(3.25±1.53)g/L]、Na+变化[(3.58±1.27)mmol/L]、冲洗时间[(30.06±6.22)h]、留置尿管时间[(47.61±13.55)h]明显优于TURP组[(4.77±1.67)g/L、(9.67±2.67)mmol/L、(58.32±10.25)h、(68.01±9.69)h](P0.05),DIOD组术后PSA下降大于TURP组[(2.34±1.29)μg/L vs(1.09±0.72)μg/L,P0.05];80 ml组中DIOD组术后PSA下降大于TURP组[(3.35±1.39)μg/L vs(1.76±0.91)μg/L,P0.05)],且围手术期各项指标明显优于TURP组(P0.05或P0.01)。DIOD组无输血、经尿道电切综合征、尿道狭窄等并发症发生,但假性尿失禁发生率高于TURP组(22.70%vs 7.83%)(P0.01)。结论:DIOD治疗BPH短期疗效确切,具有出血少、恢复快、安全性高的特点。在中、大体积前列腺中优势明显,而对小体积前列腺与TURP疗效相当。
[Abstract]:Objective: to compare the clinical effects of transurethral semiconductor laser enucleation of the prostate (DIOD) and electroprostatectomy (TURP) in the treatment of benign prostatic hyperplasia (BPH) with different volumes. Methods: a retrospective analysis of 256 patients with BPH admitted from March 2012 to August 2015 in our hospital was made, of which 141 cases were treated with DIOD,115 and TURP. was used. According to the volume of prostate, 42 cases were divided into 3 groups according to the volume of prostate, 42 cases were treated with DIOD, 31 cases were treated with TURP, 31 cases were treated with TURP, 51 cases were treated with DIOD, 45 cases were treated with TURP, 48 cases were treated with DIOD and 39 cases with TURP. The mean operative time, the change rate of hemoglobin and Na, the time of bladder irrigation, the time of indwelling urinary catheter, the preoperative and postoperative serum PSA,IPSS score, the maximum urinary flow rate (Qmax),) residual urine (PVR) and so on were all changed in each group. 缁撴灉:60 ml缁勫洿鎵嬫湳鏈熷悇椤规寚鏍囧強鏈悗闅忚鎸囨爣鍦ㄤ袱绉嶆墜鏈柟娉曢棿鏃犳槑鏄惧樊寮,

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