热淋清颗粒对肾结石术后尿路感染的预防及促排石、止痛效果观察

发布时间：2018-09-15 05:41

【摘要】：目的:探讨热淋清颗粒对肾结石术后尿路感染的预防作用及对术后排石、疼痛的影响。方法:选择2012年5月—2015年4月接受手术治疗的72例肾结石患者,按照随机数字表法分为对照组与观察组各36例,对照组术后静滴盐酸左氧氟沙星氯化钠注射液干预,观察组在此基础上加用热淋清颗粒治疗,两组均治疗1周,观察两组治疗效果,统计结石排出率及排净时间,观察患者尿痛、尿频、血尿、肾区疼痛、叩击痛等症状及体征评分改善情况,监测治疗期间不良反应发生情况,记录两组术后1个月内尿路感染发生率。结果:1观察组总有效率略高于对照组,但对比差异无统计学意义(P0.05);2观察组治疗1周血尿、尿频、尿痛、尿急、肾区疼痛、叩击痛等症状积分均低于对照组,对比差异有统计学意义(P0.05);3观察组结石排出率高于对照组(P0.05),结石排净时间短于对照组,对比差异有统计学意义(P0.05);4两组治疗期间不良反应发生率相近(P0.05),均未见严重不良反应;5观察组尿路感染发生率低于对照组,对比差异有统计学意义(P0.05)。结论:热淋清颗粒用于防治PCNL术后尿路感染整体效果好,可促进结石排出,减轻尿痛、肾区疼痛等症状,且安全性高,不良反应少。
[Abstract]:Objective: to investigate the preventive effect of Rilinqing granule on urinary tract infection after renal calculi and its effect on postoperative lithotomy and pain. Methods: 72 patients with renal calculi received surgical treatment from May 2012 to April 2015 were divided into control group (n = 36) and observation group (n = 36). The control group received intravenous drip of levofloxacin hydrochloride sodium chloride injection after operation. On this basis, the observation group was treated with Rilinqing granules, both of them were treated for 1 week. The therapeutic effect of the two groups was observed, the stone excretion rate and the time of excretion were counted, and the patients' urinary pain, frequency of urine, hematuria and pain in the renal area were observed. The score of percussion pain and other symptoms and signs were improved, adverse reactions during treatment were monitored, and the incidence of urinary tract infection within 1 month after operation was recorded in both groups. Results the total effective rate of the observation group was slightly higher than that of the control group, but the difference was not statistically significant (P0.05) the scores of hematuria, frequency of urine, urinal pain, urinal urgency, renal area pain and percussion pain in the observation group were lower than those in the control group. The difference was statistically significant (P0.05). The stone excretion rate in the observation group was higher than that in the control group (P0.05), and the time of stone drainage was shorter than that in the control group. The difference was statistically significant (P0.05) the incidence of adverse reactions in the two groups during treatment was similar (P0.05), and the incidence of urinary tract infection in the observation group was lower than that in the control group (P0.05). Conclusion: Rilinqing granule is effective in the prevention and treatment of urinary tract infection after PCNL. It can promote the excretion of stone and relieve the symptoms of urinary pain and renal pain. It is safe and has less adverse reactions.
【作者单位】：余姚市人民医院泌尿外科;
【分类号】：R699.2

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