休闲体育运动与上尿路结石风险的关联性研究

发布时间：2018-11-03 19:16

【摘要】：[目的]上尿路结石是一种与多种风险因素相关联的复杂性疾病,但是休闲运动在上尿路结石形成中扮演的角色尚未明确,为了探索他们的关系,我们在亚洲人群中展开了一项横断面研究。[方法]病例组来源于广西地区12所公立医院泌尿外科诊断为上尿路结石的住院病人,选取参加当地医疗中心健康体检的人群作为对照组进行横断面观察研究,通过相同的标准调查问卷采集每一位研究对象的基本信息和生活行为资料,使用代谢当量评分(METs)量化评估研究对象每周运动量。运用分层分析、多因素条件logistic回归比较分层后每周休闲运动量后与上尿路结石形成风险的关联。[结果]总共纳入对照组成员1782名、病例组1517名。经过矫正年龄、民族、BMI、收缩压、饮水量和痛风、糖尿病、高血压、额外补充钙剂等病史,每周参加较多休闲体育运动的人群(PA5 9.9;10 19.9;20 29.9;30METs/wk)相对于每周参加较低休闲运动的人群(PA≤4.9 METs/wk),伴随着较低的上尿路结石发病风险(aOR=0.15,0.32,0.24,0.34;95%CI=0.08 0.15,0.23 0.43,0.15 0.40,0.22 0.53;P0.001)。[结论]在我们的横断面研究中,休闲体育运动,尤其是每周低到中度体育运动量与降低的上尿路结石形成风险相关。
[Abstract]:[objective] Upper urinary calculi are a complex disease associated with multiple risk factors, but the role of leisure exercise in the formation of upper urinary calculi is not clear, in order to explore their relationship, We conducted a cross-sectional study in Asian populations. [methods] the case group came from 12 public hospitals in Guangxi. The patients who were diagnosed as upper urinary calculi in urology department were selected as the control group. The basic information and life behavior data of each of the subjects were collected by the same standard questionnaire, and the amount of exercise per week was quantitatively evaluated by metabolic equivalent score (METs). Using stratification analysis, multivariate conditional logistic regression was used to compare the relationship between the weekly leisure exercise after stratification and the risk of upper urinary tract stone formation. [results] A total of 1782 members were included in the control group and 1517 in the case group. After correcting the history of age, nationality, BMI, systolic blood pressure, drinking water and gout, diabetes mellitus, hypertension, additional calcium supplement and so on, the people who participated in more leisure sports every week (PA5 9. 9 ~ 10 ~ 19. 9 ~ 20 + 29. 9); 30METs/wk) was associated with a lower risk of upper urinary calculi (aOR=0.15,0.32,0.24,0.34;) compared to those who participated in lower leisure activities per week (PA 鈮，

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