激光汽化术与前列腺电切术治疗良性前列腺增生疗效的Meta分析

发布时间：2018-11-18 06:15

【摘要】：目的系统评价经尿道980nm激光汽化术与前列腺电切术(TURP)治疗良性前列腺增生(BPH)的疗效。方法收集国内外关于经尿道980nm激光汽化术与TURP治疗BPH的文献,采用Revman5.3软件进行Meta分析。结果筛选后共6篇文献符合纳入标准,总计839例,其中包括980nm激光治疗组450例和TURP组389例。Meta结果显示:和TURP组相比,980nm激光组手术时间差异无统计学意义[标准化均数差(SMD)=0.11,95%CI(-0.52,0.74),P0.05],住院时间较短[SMD=-1.95,95%CI(-3.42,-0.48),P0.05]及术后尿管留置时间较短[SMD=-2.64,95%CI(-3.92,-1.36),P0.05]。980 nm激光组和TURP组在术后国际前列腺症状评分(IPSS)差异无统计学意义[加权均数差(WMD)=0.12,95%CI(-0.27,0.51),P0.05],术后生活质量评分(QOL)评分差异无统计学意义[SMD=0.00,95%CI(-0.57,0.57),P0.05],术后最大尿流率(Qmax)差异无统计学意义[SMD=0.06,95%CI(-0.26,0.37),P0.05]。结论 980nm激光治疗良性BPH与经典的TURP术式相比,在住院时间和术后尿管留置时间方面有优势,远期效果无明显差异。
[Abstract]:Objective to evaluate the efficacy of transurethral 980nm laser vaporization and electroprostatectomy (TURP) in the treatment of benign prostatic hyperplasia (BPH). Methods the literature about transurethral 980nm laser vaporization and TURP for BPH were collected and analyzed with Revman5.3 software. Results A total of 839 cases, including 450 cases of 980nm laser therapy group and 389 cases of TURP group, met the inclusion criteria. The Meta results showed that: compared with the TURP group, the results of Meta showed that: 1. There was no significant difference in operation time in 980nm laser group [standardized mean difference (SMD) = 0.1195 CI (-0.52U 0.74), P0.05], and the duration of hospitalization was shorter [SMD=-1.95,95%CI (-3.42 卤0.48)]. The duration of urethral catheterization was shorter [SMD=-2.64,95%CI (-3.92mg-1.36)], There was no significant difference in the international prostatic symptom score (IPSS) between the 980 nm laser group and the TURP group (weighted mean difference (WMD) = 0.120.95 CI (-0.27 卤0.51), P0.05). There was no significant difference in (QOL) score of postoperative quality of life [SMD=0.00,95%CI (-0.57 卤0.57), P0.05], but there was no significant difference in (Qmax) of postoperative maximum urinary flow rate [SMD=0.06,95%CI (-0.26 卤0.37)]. P0.05]. Conclusion 980nm laser therapy for benign BPH has advantages in terms of hospitalization time and urinary catheter indwelling time compared with the classic TURP procedure, but there is no significant difference in long-term effect.
【作者单位】：中南大学湘雅医院国际医疗部外科;
【基金】：湖南省自然科学基金(No:14JJ7004)
【分类号】：R699.8

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