肾福康胶囊治疗肾功能不全的临床研究
发布时间：2018-11-20 06:06
【摘要】：目的:探讨肾福康胶囊治疗肾功能不全患者的临床疗效及对肾功能指标的影响。方法:对广西医科大学第一附属医院2015年2-5月使用肾福康胶囊治疗肾功能不全的住院患者100例进行回顾性分析,记录患者一般情况、治疗方案、治疗前后的肾功能指标和临床疗效,并分析临床疗效与年龄、疗程的关系。结果:急性肾功能不全33例,慢性肾功能不全67例。肾福康胶囊的给药方式主要是口服给药(97例,97.00%),剂量主要为6粒/d(36例,36.00%),疗程以0~7 d(39例)和7~15 d(49例)为主。治疗后,所有患者的血清肌酐水平较治疗前显著降低,肾小球滤过率、内生肌酐清除率较治疗前显著升高,差异有统计学意义(P0.05)。患者总有效率为72.00%,其中急性肾功能不全患者有效率为87.88%,显著高于慢性肾功能不全患者的64.18%,差异有统计学意义(P0.05)。≤60岁患者中,急性肾功能不全患者的总有效率显著高于慢性肾功能不全患者,差异有统计学意义(P0.05);60岁急、慢性肾功能不全患者疗效比较,差异无统计学意义(P0.05);慢性肾功能不全患者中,60岁患者的总有效率显著高于≤60岁患者,差异有统计学意义(P0.05)。随着疗程延长,急性肾功能不全患者的总有效率呈上升趋势,慢性肾功能不全患者的总有效率先升高后下降。所有患者治疗期间均未见明显不良反应的发生。结论:肾福康胶囊可改善肾功能不全患者的肾功能,对急性肾功能不全患者临床疗效优于慢性肾功能不全患者,且安全性好;其临床疗效可能与年龄、疗程有关。
[Abstract]:Objective: to investigate the effect of Shenfukang capsule on renal function index. Methods: 100 inpatients with renal insufficiency were treated with Shenfukang capsule from February to May 2015 in the first affiliated Hospital of Guangxi Medical University. The indexes of renal function and clinical efficacy before and after treatment were analyzed, and the relationship between clinical efficacy and age and course of treatment was analyzed. Results: there were 33 cases of acute renal insufficiency and 67 cases of chronic renal insufficiency. Shenfukang capsule was administered orally (97 cases, 97.00%), the dosage was mainly 6 tablets / d (36 cases, 36.00%). The course of treatment was 0 days (39 cases) and 715 days (49 cases). After treatment, the serum creatinine level of all patients was significantly lower than before treatment, glomerular filtration rate, creatinine clearance rate was significantly higher than before treatment, the difference was statistically significant (P0.05). The total effective rate was 72.00, in which the effective rate of acute renal insufficiency was 87.88, which was significantly higher than that of chronic renal insufficiency (64.18). The difference was statistically significant (P0.05). The total effective rate of patients with acute renal insufficiency was significantly higher than that of patients with chronic renal insufficiency (P0.05). There was no significant difference in the curative effect of 60 years old patients with acute renal failure and chronic renal insufficiency patients (P0.05); the total effective rate of 60 years old patients with chronic renal insufficiency was significantly higher than that of 鈮，
本文编号：2344002
[Abstract]:Objective: to investigate the effect of Shenfukang capsule on renal function index. Methods: 100 inpatients with renal insufficiency were treated with Shenfukang capsule from February to May 2015 in the first affiliated Hospital of Guangxi Medical University. The indexes of renal function and clinical efficacy before and after treatment were analyzed, and the relationship between clinical efficacy and age and course of treatment was analyzed. Results: there were 33 cases of acute renal insufficiency and 67 cases of chronic renal insufficiency. Shenfukang capsule was administered orally (97 cases, 97.00%), the dosage was mainly 6 tablets / d (36 cases, 36.00%). The course of treatment was 0 days (39 cases) and 715 days (49 cases). After treatment, the serum creatinine level of all patients was significantly lower than before treatment, glomerular filtration rate, creatinine clearance rate was significantly higher than before treatment, the difference was statistically significant (P0.05). The total effective rate was 72.00, in which the effective rate of acute renal insufficiency was 87.88, which was significantly higher than that of chronic renal insufficiency (64.18). The difference was statistically significant (P0.05). The total effective rate of patients with acute renal insufficiency was significantly higher than that of patients with chronic renal insufficiency (P0.05). There was no significant difference in the curative effect of 60 years old patients with acute renal failure and chronic renal insufficiency patients (P0.05); the total effective rate of 60 years old patients with chronic renal insufficiency was significantly higher than that of 鈮，
本文编号：2344002
本文链接：https://www.wllwen.com/yixuelunwen/mjlw/2344002.html
最近更新
教材专著
