肾移植术后尿路感染病原菌及抗感染治疗方案分析

发布时间：2018-11-23 13:28

【摘要】：目的:探讨肾移植术后尿路感染的发生时间、主要病原菌、耐药性及抗感染治疗方案,为临床诊治提供参考。方法:将2013年1月-2015年12月因肾移植术后尿路感染来某院就诊的59例患者作为研究对象,对其临床资料进行回顾性分析。结果:肾移植术后尿路感染的发生时间主要集中在术后6个月内,占88.14%。病原体主要为细菌和病毒,其中革兰阴性菌感染42例,占65.63%,革兰阳性菌感染11例,占17.19%,巨细胞病毒感染8例,占12.50%,真菌感染3例,占4.69%。经验性抗感染治疗药物主要包括哌拉西林他唑巴坦、头孢哌酮舒巴坦等。结论:肾移植术后尿路感染的发生率较高,需引起重视,应根据患者的具体情况,合理用药,提高治愈率。
[Abstract]:Objective: to investigate the occurrence time, main pathogenic bacteria, drug resistance and anti-infection treatment of urinary tract infection after renal transplantation, so as to provide reference for clinical diagnosis and treatment. Methods: the clinical data of 59 patients with urinary tract infection after renal transplantation from January 2013 to December 2015 were retrospectively analyzed. Results: the time of urinary tract infection after renal transplantation was mainly within 6 months after transplantation, accounting for 88.14. The pathogens were mainly bacteria and viruses, of which 42 cases were Gram-negative bacteria (65.63%), 11 cases were Gram-positive bacteria (17.19%), 8 cases were cytomegalovirus (12.50%), 3 cases were fungal infections (4.69%). Empirical anti-infection drugs include piperacillin, cefoperazone and sulbactam. Conclusion: the incidence of urinary tract infection after renal transplantation is high and should be paid attention to.
【作者单位】：首都医科大学附属北京朝阳医院药事部;
【分类号】：R699.2

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