输尿管软镜取石治疗老年上段嵌顿输尿管结石患者的效果

发布时间：2018-12-24 21:05

【摘要】：目的探讨不同途径取石治疗嵌顿性输尿管上段结石的治疗效果及对患者创伤程度的影响。方法 80例嵌顿性输尿管上段结石患者分为经皮肾输尿管取石(MPCNL)的对照组和经尿道输尿管取石(URL)的观察组各40例,比较两种手术方式的治疗效果及两种手术方式对患者炎症因子和应激水平的影响。结果手术后1d观察组患者丙二醛(MDA)、晚期氧化蛋白产物(AOPP)分别为(21.54±1.20)、(58.63±4.15)μmol/L,术后3、5dMDA、AOPP水平持续下降,均低于对照组患者;术后1d观察组谷胱目肽过氧化物酶(GSH-PX)、超氧化物歧化酶(SOD)分别为(197.53±16.65)、(17.54±1.63)μg/mL,术后3、5d GSH-PX、SOD水平持续上升均高于对照组患者,术后1d观察组肿瘤坏死因子α(TNF-α)、白细胞介素10(IL-10)水平分别为(33.34±5.17)、(56.54±6.63)μg/mL,术后3、5d持续下降,均明显低于对照组患者,差异有统计学意义(P0.05)。结论采用URL治疗嵌顿性输尿管上段结石对机体创伤较小,取石成功率高,值得临床推广运用。
[Abstract]:Objective to investigate the effect of stone extraction in the treatment of incarcerated upper ureteral calculi and its influence on the degree of trauma. Methods Eighty patients with incarcerated upper ureteral calculi were divided into two groups: the control group (MPCNL) and the observation group (40 cases) with transurethral ureteral lithotripsy (URL). To compare the therapeutic effects of two surgical methods and their effects on inflammatory factors and stress levels. Results the level of malondialdehyde (MDA) (MDA), late oxidative protein (AOPP) was (21.54 卤1.20), (58.63 卤4.15) 渭 mol/L, in the observation group on the 1st day after operation, which was significantly lower than that in the control group. Glutathione peroxidase (GSH-PX) and superoxide dismutase (SOD) were (197.53 卤16.65), (17.54 卤1.63) 渭 g 路mL ~ (-1) 渭 g 路mL ~ (-1) in the observation group on the 1st day after operation. The GSH-PX,SOD level in the observation group was significantly higher than that in the control group on the 3rd and 5th day after operation. The levels of tumor necrosis factor 伪 (TNF- 伪) and interleukin-10 (IL-10) were (33.34 卤5.17), (56.54 卤6.63) 渭 g / mL in the observation group on the 1st day after operation. The levels of tumor necrosis factor 伪 (TNF- 伪) and interleukin 10 (IL-10) in the observation group were (33.34 卤5.17), () 56.54 卤6.63 渭 g / mL respectively. The difference was statistically significant (P0.05). Conclusion the treatment of incarcerated upper ureteral calculi with URL has less injury and higher success rate, so it is worth popularizing.
【作者单位】：贵州航天医院泌尿外科;
【分类号】：R699.4

【相似文献】