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原发性肾病综合征患者低T3综合征的发病因素分析

发布时间:2018-12-29 10:25
【摘要】:目的分析原发性肾病综合征(PNS)患者低T3综合征(LT3S)的发病因素。方法 195例PNS患者按是否合并LT3S分为并发者43例(并发LT3S)和正常者152例(甲状腺功能正常),单因素分析法比较两者临床资料,多因素Logistics回归分析法分析PNS患者并发LT3S的相关因素。结果单因素分析显示,PNS患者并发LT3S者和甲状腺功能正常者活化部分凝血酶时间、血清白蛋白、24 h尿蛋白定量、CD36、血小板聚集率(PAg TADP、PAg TAA)比较有统计学差异(P均0.05)。多因素分析显示,CD36、PAg TAA为PNS患者并发LT3S的相关因素。结论 PNS患者易并发LT3S,CD36、PAg TAA为PNS患者并发LT3S的相关因素。
[Abstract]:Objective to analyze the risk factors of low T 3 syndrome (LT3S) in patients with primary nephrotic syndrome (PNS). Methods one hundred and fifty-five patients with PNS were divided into three groups according to whether they were complicated with LT3S: 43 cases (complicated with LT3S) and 152 cases with normal thyroid function (normal thyroid function). The clinical data were compared by univariate analysis. Multivariate Logistics regression analysis was used to analyze the related factors of LT3S in PNS patients. Results univariate analysis showed that the activated partial thrombin time, serum albumin, 24 h urinary protein quantification and platelet aggregation rate of CD36, were found in patients with PNS complicated with LT3S and normal thyroid function. There was a significant difference in PAg TAA) between the two groups (P < 0. 05). Multivariate analysis showed that CD36,PAg TAA was associated with LT3S in PNS patients. Conclusion the risk of LT3S,CD36,PAg TAA in PNS patients is related to LT3S in PNS patients.
【作者单位】: 南通大学附属医院;
【基金】:南通市重点科技项目(MS32015018)
【分类号】:R692

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