成人肾小球微小病变的病理特征

发布时间：2019-03-18 16:05

【摘要】：目的探讨成人肾小球微小病变(minimal change disease,MCD)的临床病理学特点。方法回顾性分析符合肾病综合征(nephrotic syndrome,NS)、肾活检病理诊断为MCD、年龄≥18周岁的162例成人患者的病理特征。结果对162例成人MCD肾组织病理改变进行统计发现,肾小球球性硬化、肾间质纤维化、肾间质炎细胞浸润、肾小管萎缩、肾血管病变的比率分别为32.7%、42.6%、55.6%、45.7%、37.0%,除肾间质炎细胞浸润,余病理改变的比率均随着年龄的增长而增加。经年龄纠正后,肾小球球性硬化的比率与患者年龄的关联消失。结论成人MCD病理改变随年龄增长,病变比例及严重程度均增高。
[Abstract]:Objective to investigate the clinicopathological features of adult glomerulonephritis (minimal change disease,MCD). Methods the pathological features of renal biopsy were retrospectively analyzed in 162 adult patients with nephrotic syndrome (nephrotic syndrome,NS) who were diagnosed by renal biopsy as MCD, 鈮，

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