泌尿外科住院患者PSA检查的临床意义

发布时间：2019-05-11 03:10

【摘要】：目的: 探讨泌尿外科男性住院患者前列腺特异性抗原(Prostate specific antigen,PSA)检查的价值和临床意义。 方法: 选取2010.12-2013.12来我科45岁以上，常规检查PSA的男性住院患者1354例。年龄45~95岁，，平均年龄为（68±11.19）岁。排除临床已确诊前列腺癌及由于各种原因不能配合者。对1354例患者PSA的检查结果进行分析，PSA水平、年龄、入院诊断、出院诊断、肛门指检、影像学检查、穿刺病理结果等临床资料进行分析，探讨PSA检查的价值。 结果: 在1354例研究对象中，PSA异常共439例，PSA正常共915例，共确诊前列腺癌患者91例。随着年龄的增长，前列腺癌的发病率也逐步增高，其整体差异有统计学意义（X2=33.827，P＜0.05），但组间差异无统计学意义。73例前列腺癌患者（79.3%）集中在60~79岁之间。随着PSA水平升高，前列腺活检的阳性率也随之升高，其整体差异有统计学意义（X2=68.797，P＜0.05）。但PSA正常组与PSA异常组间的穿刺阳性率的差异无统计学意义。年龄与PSA水平也有一定的相关性，年龄越到，PSA水平越高。91例前列腺癌中以下尿路症状（lowerurinary tract symptoms,LUTS）为首发症状就诊的患者为83例（91.2%），以非LUTS为首发症状就诊的患者为8例（8.8%）。以良性疾病为初步诊断最终确诊前列腺癌患者25例，肿瘤分期较早，以怀疑前列腺癌为初步诊断最终确诊前列腺癌患者66例，肿瘤分期较晚。 结论: 泌尿外科住院患者行PSA检查有较重要的临床意义，对于无明显临床症状前列腺癌的早期诊断尤为重要，建议50岁以上的男性住院患者应筛查PSA。
[Abstract]:Objective: to investigate the value and clinical significance of prostate specific antigen (Prostate specific antigen,PSA) in male inpatients in urology. Methods: 1354 male inpatients over 45 years old and undergoing routine examination of PSA were selected from December 2012 to March 12, 2013.2010.Results: 1354 male inpatients over 45 years old were enrolled in this study. The average age was (68 卤11.19) years old. Exclude those who have been clinically diagnosed with prostate cancer and are unable to cooperate for various reasons. The clinical data of 1354 patients with PSA, such as PSA level, age, admission diagnosis, discharge diagnosis, anal finger examination, imaging examination and puncture pathological results, were analyzed to explore the value of PSA examination. Results: among 1354 subjects, 439 cases were abnormal PSA, 915 cases were normal PSA, and 91 cases were diagnosed as prostate cancer. With the increase of age, the incidence of prostate cancer also increased gradually, and the overall difference was statistically significant (X2 鈮

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