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肾错构瘤破裂出血的临床风险因素分析

发布时间:2019-05-22 12:31
【摘要】:目的探讨肾错构瘤(RAML)破裂出血的临床风险因素。方法收集有完整病史及肾脏影像学资料的RAML患者352例,将与错构瘤破裂出血可能有关的风险因素行破裂出血组和未破裂出血组间的单因素分析及多因素logistic回归分析。结果 352例患者中有41例患者的错构瘤发生破裂出血,311例未发生破裂出血。通过单因素分析,发现年龄、有无临床表现、结节性硬化症、高血压、瘤体是否突出肾表面、错构瘤大小(4 cm或≥4 cm)以及肿瘤血管是否丰富等因素在两组间具有明显的差异(P0.05);再通过多因素logistic回归分析进一步发现,有临床表现(OR=36.012,P=0.000)、伴随有结节性硬化症(OR=25.167,P=0.004)、瘤体突出肾脏表面(OR=8.151,P=0.003)、错构瘤大小≥4 cm(OR=13.006,P=0.003)、肿瘤血管丰富(OR=4.272,P=0.004)等因素对破裂出血的影响有显著的统计学意义。结论有临床表现者、伴随有结节性硬化症、肿瘤外生性生长、瘤体≥4 cm以及丰富的肿瘤血管等因素可视为RAML破裂出血的高风险因素。
[Abstract]:Objective to investigate the clinical risk factors of (RAML) rupture and hemorrhage in renal hamartoma. Methods 352patients with complete history and renal imaging data were collected. The risk factors related to ruptured hemorrhage of hamartoma were analyzed by univariate analysis and multivariate logistic regression analysis between ruptured bleeding group and unruptured hemorrhage group. Results there were 41 patients with hamartoma ruptured bleeding and 311 patients without ruptured hemorrhage. Through univariate analysis, it was found that age, clinical manifestations, nodular sclerosis, hypertension and protruding renal surface were found. There were significant differences in the size of hamartoma (4 cm or 鈮,

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