益肾利湿化瘀法结合B超引导下穿刺抽液硬化术治疗单纯性肾囊肿的远期疗效观察

发布时间：2019-06-29 22:43

【摘要】：目的:观察益肾利湿化瘀法结合B超引导下穿刺抽液硬化术治疗单纯性肾囊肿的远期疗效是否优于单纯穿刺抽液硬化术。方法:使用随机、对照设计,对直径4cm的单纯性肾囊肿进行干预治疗,对比两组,即B超引导下穿刺抽液硬化术(对照组)和加用益肾利湿化瘀法中药汤剂口服治疗28天(治疗组),统计3、6、12个月后的疗效及复发率。结果:肾囊肿穿刺前:治疗组(n=27)、对照组(n=26)囊肿的直径分别为(6.66土1.90)cm、(6.95±2.10)cm(P0.05),囊肿的体积分别为(129.60±121.50)ml、(144.41±137.94)ml(P0.05);经穿刺后,治疗组、对照组囊肿的体积分别为(19.54±10.68)ml、(22.82±9.51)ml(P0.05)。3、6、12个月后复查:治疗组囊肿的体积为(6.81 土9.41)ml、(6.81±12.05)ml、(7.08±19.54)ml,明显小于穿刺后的体积(19.54±10.68)ml(P0.05);对照组 3、6、12 个月后复查囊肿体积为(41.07±78.92)ml、(42.83±88.40)ml、(46.85±90.17)ml,与穿刺后的体积(22.82±9.51)ml 存在显著差异(P0.05);经治疗12个月后治疗组囊肿直径为(1.71±1.50)cm,囊肿体积为(7.08±19.54)ml与对照组囊肿直径(3.99±2.34)cm,囊肿体积(46.85±90.17)ml相比均存在明显差异(P0.05);且治疗组患者总有效率为96.29%,明显高于对照组患者总有效率69.23%(P0.05),说明治疗组在远期疗效上明显优于对照组。在复发率方面,治疗组(3.70%)较对照组(37.77%)存在明显差异(P0.05),表明在中药干预治疗后单纯性肾囊肿远期复发率明显降低。在症状改善方面,治疗组改善率92.86%,对照组88.89%,两组在症状改善方面均有很好疗效。两者均无明显不良反应。关于单纯性肾囊肿是否影响肾功能,对53例患者穿刺前和穿刺后比较后发现,肌酐、尿素氮、尿酸、及收缩压并无明显差异(P0.05)。结论:采用益肾利湿化瘀法结合B超穿刺抽液硬化术其远期疗效明显优于单纯使用穿刺抽液硬化术治疗单纯性肾囊肿(直径4cm者)。
[Abstract]:Objective: to observe whether the long-term effect of invigorating kidney, promoting dampness and removing blood stasis combined with B-ultrasound guided puncture and drainage sclerosis in the treatment of simple renal cysts is better than that of simple puncture and drainage sclerosis. Methods: simple renal cysts with diameter 4cm were treated with random and controlled design. The curative effect and recurrence rate after 12 months of treatment were compared between the two groups, namely, B-ultrasound guided puncture and drainage sclerosis (control group) and oral treatment with Yishen Lishui Huayu decoction for 28 days (treatment group). Results: before puncture of renal cysts: the diameter of cysts in treatment group (n 鈮，

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