Development of a rat model of D-galactosamine/lipopolysaccha

发布时间：2021-04-02 16:53

　　AIM:To develop a practical and reproducible rat model of hepatorenal syndrome for further study of the pathophysiology of human hepatorenal syndrome. METHODS:Sprague-Dawley rats were intravenously injected with D-galactosamine and lipopolysaccharide（LPS） via the tail vein to induce fulminant hepatic failure to develop a model of hepatorenal syndrome. Liver and kidney function tests and plasma cytokine levels were measured after D-galactosamine/LPS administration,and hepatic and renal pathology w... 

【文章来源】：World Journal of Gastroenterology. 2015,21(34)SCI

【文章页数】：9 页

【参考文献】：
期刊论文
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