术前中性粒细胞与淋巴细胞比值预测可切除泌尿系肿瘤预后的价值:系统综述和荟萃分析(英文)
发布时间:2021-04-24 14:31
目的术前中性粒细胞与淋巴细胞比值(NLR)与多种恶性肿瘤的预后密切相关,但是,NLR对可切除泌尿系肿瘤预后的影响尚不确定。因此,此系统综述和荟萃分析旨在探讨术前NLR在预测可切除泌尿系肿瘤预后方面的价值。方法我们通过检索Embase、PubMed/MEDLINE和Cochrane数据库,依据纳入和排除标准筛选文献,最终纳入25项研究,其中包括15950例受试对象。采用风险比(HRs)及其95%可信区间(CIs)评估术前NLR与可切除泌尿系肿瘤患者的总生存期(OS)及肿瘤特异性生存期(CSS)的关系。结果结果表明对于患有可切除泌尿系恶性肿瘤的患者,术前NLR能预测其预后。NLR越高,患者的OS(HR=1.40,95%CI:1.26~1.54,P<0.001)和CSS越短(HR=1.43,95%CI:1.27~1.59,P<0.001)。此外,不论患者种族或术前NLR阈值高低,术前NLR升高均能提示肾细胞癌(OS:HR=2.06,95%CI=1.54~2.76,P=0.131;CSS:HR=2.46,95%CI=1.46~4.16,P=0.178)、上尿路上皮癌(OS:HR=1...
【文章来源】:Chinese Medical Sciences Journal. 2020,35(03)CSCD
【文章页数】:10 页
【文章目录】:
MATERIALS AND METHODS
Literature search
Inclusion and exclusion criteria
Data extraction and quality control
Statistical analysis
RESULTS
Characteristics of the included studies
Overall survival
Cancer-specific survival
Heterogeneity
Publication bias
DISCUSSION
Conflict of Interests Statement
本文编号:3157529
【文章来源】:Chinese Medical Sciences Journal. 2020,35(03)CSCD
【文章页数】:10 页
【文章目录】:
MATERIALS AND METHODS
Literature search
Inclusion and exclusion criteria
Data extraction and quality control
Statistical analysis
RESULTS
Characteristics of the included studies
Overall survival
Cancer-specific survival
Heterogeneity
Publication bias
DISCUSSION
Conflict of Interests Statement
本文编号:3157529
本文链接:https://www.wllwen.com/yixuelunwen/mjlw/3157529.html
最近更新
教材专著