脊椎段老龄化对椎骨皮质骨力学行为的影响分析

发布时间：2018-08-09 19:04

【摘要】：椎骨皮质骨的断裂风险会随着年龄的增加而增大,然而目前老龄化对皮质骨断裂影响的机制尚不明确。本文的研究目的是探明脊椎段老龄化对皮质骨应变的影响规律。文中建立了2种不同程度老龄化(中度老龄化和完全老龄化)的有限元脊椎段模型,这些老龄化的脊椎段模型是通过改变椎间盘的几何形状和脊椎各组成部分的材料属性生成的,然后将它们与作者之前研究中的一个健康脊椎段有限元模型进行了对比。为了研究哪一种情况对皮质骨的应变影响更大,本文分别建立了两种有限元模型比较方式:一种只改变脊椎材料属性,另一种只改变椎间盘的几何形状。研究结果表明,皮质骨的应变随着老龄化而增大;相比于椎间盘几何形状改变,脊椎材料属性的改变对皮质骨应变的影响更大。本研究结果或可说明,对于预防和治疗椎骨皮质骨断裂,增强脊椎强度是更有效的方式。
[Abstract]:The risk of fracture of cortical bone increases with age, but the mechanism of aging on fracture of cortical bone is unclear. The purpose of this study is to investigate the effect of spinal segment aging on cortical bone strain. In this paper, two kinds of finite element spinal segment models with different degrees of aging (moderate aging and complete aging) are established. These aging spinal segment models were generated by changing the geometric shape of the intervertebral disc and the material properties of each component of the vertebra and were compared with a healthy spinal segment finite element model previously studied by the authors. In order to find out which condition has more influence on cortical bone strain, two finite element models are established: one is to change the properties of vertebral material and the other is to change the geometric shape of intervertebral disc. The results show that the strain of cortical bone increases with aging, and the changes of vertebral material properties have more influence on the strain of cortical bone than the geometric changes of intervertebral disc. The results of this study may suggest that enhancing spinal strength is a more effective way to prevent and treat cortical fracture of vertebrae.
【作者单位】：大连理工大学工程力学系;
【基金】：中央高校基本科研业务费专项资金资助(DUT15RC(3)130)
【分类号】：R318.01;R683

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