全膝关节置换术膝关节有限元模型的构建及其力学分析

发布时间：2018-08-12 11:22

【摘要】：目的通过多模态CT和MRI影像数据构建复杂人体膝关节有限元模型的研究较少。文中旨在通过CT和MRI影像数据配准融合构建全膝关节置换术(TKA)膝关节有限元模型,进行有限元分析,为TKA膝关节生物力学仿真研究提供模型。方法采集连云港市第一人民医院关节外科2016年6月1例26岁正常成年男性左侧膝关节CT和MRI影像数据,导入至Mimics软件构建膝关节骨性和非骨性结构三维模型。以外部参照点进行模型配准,融合成膝关节三维整体模型。仿真植入TKA假体组件,构建TKA膝关节三维模型,进一步网格划分,构建TKA膝关节三维有限元模型。对其定义材料属性、确定边界条件和载荷后,进行有限元分析。结果通过CT和MRI影像配准融合构建出包含骨骼、韧带、假体、聚乙烯衬垫和骨水泥层的TKA膝关节有限元模型,模型保持了TKA膝关节内不同结构的空间位置关系。有限元分析结果显示了TKA膝关节内的应力分布特征。TKA膝关节内外侧间室股骨假体与聚乙烯衬垫发生接触,内外侧间室接触总面积为230 mm2,内侧间室为124mm2,外侧间室为106mm2,内侧间室接触面积约为外侧间室的1.17倍。内侧间室聚乙烯上表面的压应力峰值为15.72 MPa,外侧间室聚乙烯上表面的压应力峰值为14.45 MPa,内侧间室压应力峰值是外侧间室的1.09倍。结论基于CT和MRI影像数据配准融合构建的TKA膝关节有限元模型为研究TKA膝关节生物力学行为提供了可靠工具。
[Abstract]:Objective to construct a complex finite element model of knee joint based on multimodal CT and MRI images. The purpose of this paper is to construct the finite element model of (TKA) knee joint for total knee arthroplasty by CT and MRI image registration fusion, and to provide a model for the biomechanical simulation of TKA knee joint. Methods CT and MRI images of left knee joint were collected from a 26-year-old adult male in June 2016 in the first people's Hospital of Lianyungang City. The data were imported into Mimics software to construct a three-dimensional model of bone and non-bone structure of knee joint. The model was registered with external reference point and fused into a three-dimensional global model of knee joint. The three-dimensional model of TKA knee joint was constructed by imitating the TKA prosthesis component, and then the three-dimensional finite element model of TKA knee joint was constructed by further mesh division. After defining the properties of materials, determining the boundary conditions and loads, the finite element analysis is carried out. Results the finite element model of TKA knee joint including bone, ligament, prosthesis, polyethylene pad and bone cement layer was constructed by CT and MRI image registration fusion. The model maintained the spatial relationship of different structures in TKA knee joint. The results of finite element analysis showed that the stress distribution in TKA knee joint. The total contact area was 230mm ~ 2, 124mm ~ 2 for medial room and 106mm ~ 2 for lateral room. The contact area of medial interroom was 1.17 times of that of lateral room. The peak value of compressive stress on the upper surface of the inner chamber was 15.72 MPA, and on the upper surface of the outer chamber was 14.45 MPA. The peak value of the compressive stress of the inner chamber was 1.09 times that of the outer chamber. Conclusion the finite element model of TKA knee joint based on CT and MRI image data registration fusion provides a reliable tool for studying the biomechanical behavior of TKA knee joint.
【作者单位】：连云港市第一人民医院关节外科;连云港市第一人民医院重症医学科;连云港市第一人民医院疼痛科;
【基金】：国家自然科学基金(31670956) 连云港市科技局科技发展计划项目(ZD1501) 连云港市卫生科技项目(201506;QN1402)
【分类号】：R318.01;R687.4

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