医用近β型钛合金TLM的水热预钙化与生物活性

发布时间：2018-08-14 18:36

【摘要】：医用近β型钛合金TLM(Ti-25Nb-3Zr-2Sn-3Mo)具有优良的力学和生物学性能,采用CaCl2溶液对TLM合金进行水热处理,以达到预钙化的目的。TLM合金经过纯水水热处理后,表面形成了锐钛矿二氧化钛(含五氧化二铌)的纳米颗粒薄膜;采用10 mmol/L CaCl2溶液进行水热处理时,颗粒尺寸减小,检测到钙元素;当CaCl2溶液的浓度升高到100 mmol/L时,结晶颗粒消失,形成了钙的化合物薄膜。水热处理试样在模拟体液中浸泡3 d后,表面均有磷酸钙沉积物生成,前2种试样检测到磷灰石的弱衍射峰。CaCl2溶液水热处理预钙化方法可用于多孔钛及多孔钛合金的生物活性表面改性,该方法具有改性层厚度薄,消耗溶质和溶剂少,反应物扩散快,处理温度较低,工艺简便等优点。
[Abstract]:Medical near 尾 type titanium alloy TLM (Ti-25Nb-3Zr-2Sn-3Mo) has excellent mechanical and biological properties. The TLM alloy was hydrothermal treated with CaCl2 solution to achieve the purpose of pre-calcification. Anatase TIO _ 2 (containing niobium pentoxide) nanocrystalline films were formed on the surface. The particle size decreased and calcium element was detected during hydrothermal treatment with 10 mmol/L CaCl2 solution. When the concentration of CaCl2 solution increased to 100 mmol/L, The crystalline particles disappear and form a compound film of calcium. After immersion in simulated body fluid for 3 days, calcium phosphate deposits were formed on the surface of hydrothermal treatment samples. The weak diffraction peak of apatite. CaCl2 solution hydrothermal precalcification method can be used to modify the bioactive surface of porous titanium and porous titanium alloy. The method has the advantages of thin layer thickness, less solute consumption and less solvent consumption. Rapid diffusion of reactants, low treatment temperature, simple process and so on.
【作者单位】：西安交通大学生命科学与技术学院生物医学信息工程教育部重点实验室;金属多孔材料国家重点实验室;
【基金】：中央高校基本科研业务费专项资金(xjj2011096) 金属多孔材料国家重点实验室开放课题(PMM-SKL-2-2012) 国家自然科学基金(50901058)
【分类号】：R318.08;TG146.23

【参考文献】