无远处转移晚期阴茎癌的手术治疗

发布时间：2018-02-11 00:50

本文关键词： 无远处转移晚期阴茎癌手术治疗　出处：《中华男科学杂志》2017年02期 　论文类型：期刊论文

【摘要】：目的:探讨无远处转移的晚期阴茎癌的手术疗效及影响预后的因素。方法:分析2007年9月至2015年7月行阴茎切除术及淋巴结清扫术的无远处转移晚期阴茎癌8例患者的临床资料,患者年龄37~67岁,平均51.1岁,术后随访4~60个月,平均19.25个月,分析影响患者预后的因素及手术疗效。结果:术后3例存活至今,另5例死亡,死亡率62.5%,从手术到死亡时间4~13个月,平均9个月。术后无明显并发症,4例大面积缺损患者术后皮瓣均预后良好。结论:无远处转移的晚期阴茎癌患者预后不佳,淋巴结转移是影响预后的重要因素,手术是一种相对有效的治疗手段,皮瓣可以修复肿瘤切除后的大面积皮肤缺损,尚无足够资料证明综合疗法是否有效。
[Abstract]:Objective: to investigate the operative effect and prognostic factors of advanced penile carcinoma without distant metastasis. Methods: from September 2007 to July 2015, 8 cases of advanced penile carcinoma without distant metastasis underwent penectomy and lymph node dissection were analyzed. Clinical data of patients, The age of the patients was 37 ~ 67 years (mean 51.1 years). The follow-up period was 4 ~ 60 months (mean 19.25 months). The factors affecting the prognosis and the outcome of the operation were analyzed. Results: three patients survived until now, and five died, the mortality rate was 62.5 months, the time from operation to death was 413 months. The average was 9 months. The postoperative flap had a good prognosis in 4 patients with large area defect without obvious complications. Conclusion: the prognosis of the patients with advanced penile carcinoma without distant metastasis is not good. Lymph node metastasis is an important factor affecting the prognosis. Operation is a relatively effective treatment, flap can repair the large area of skin defect after tumor resection, but there is not enough data to prove whether the combined therapy is effective or not.
【作者单位】：上海交通大学医学院附属第九人民医院泌尿外科;
【基金】：国家自然科学基金(81172450) 浦东新区卫生系统重点学科群建设资助(PWZxq2014-11)~~
【分类号】：R737.27

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