腹腔镜与开腹手术治疗食管胃结合部腺癌疗效的系统分析

发布时间：2018-02-23 12:51

本文关键词： 腹腔镜食管胃结合部腺癌开腹术　出处：《新疆医科大学》2015年硕士论文　论文类型：学位论文

【摘要】：目的：评价腹腔镜手术与传统开腹手术治疗食管胃结合部腺癌(AEG)的有效性和安全性,为治疗AEG的临床方案的选择提供循证依据。方法；检索PubMed、 Web of Science、相关期刊论文、万方数据库及维普数据库等有关腹腔镜下AEG切除术、传统开腹AEG切除术术后疗效分析及对比的临床研究相关文献,按纳入和排除标准由2名研究者独立进行筛选并提取相关数据资料,对手术时间、术中出血量、术后并发症、淋巴结清除数目和术后住院时间等指标进行汇总分析。结果：腹腔镜手术时间加权均值为(182.21±42.35)min,开腹手术时间均值为(140±26)min,腹腔镜手术时间长于开腹手术时间,差异有统计学(P0.05)。腹腔镜手术的住院时间加权后为(12.7±2.8)d,开腹手术的住院时间加权为(15.0±3.0)d,差异无统计学意义。腹腔镜手术术中出血量加权均值为(96.24±68.75)ml,开腹手术为(220±58)ml,差异有统计学意义(P0.05)。腹腔镜手术淋巴结清扫数目加权均值为(26.34±5.79)枚／例,开腹手术为(28.1±1.4)枚/例,差异无统计学意义(P0.05)。结论：AEG腹腔镜手术与开腹手术比较,术中出血量少,手术时间显著长于传统开腹手术,说明AEG镜下手术操作较为复杂,需要较高的操作技术。
[Abstract]:Objective: to evaluate the efficacy and safety of laparoscopic surgery and traditional open surgery in the treatment of esophageal and gastric conjunctive adenocarcinoma (AEGG), and to provide evidence based basis for the selection of clinical regimens for the treatment of AEG. Methods: PubMed, Web of Science, full text database of Chinese journals were searched. The clinical literature on the analysis and comparison of the curative effect of laparoscopic AEG resection and traditional open AEG resection is related to Wanfang database and Weip database. According to the inclusion and exclusion criteria, the two researchers independently screened and extracted the relevant data. The operative time, intraoperative bleeding volume, postoperative complications, Results: the weighted mean time of laparoscopic surgery was 182.21 卤42.35 min, and the mean time of open surgery was 140 卤26 min. The operative time of laparoscopic surgery was longer than that of open surgery. The difference was statistically significant (P < 0.05). The weighted hospitalization time of laparoscopic surgery was 12.7 卤2.8 days, and that of open surgery was 15.0 卤3.0 days. The weighted mean of blood loss during laparoscopic surgery was 96.24 卤68.75 ng / ml, and that of laparotomy was 220 卤58ml / ml. The weighted mean of lymph node dissection in laparoscopic surgery was 26.34 卤5.79. There was no significant difference between laparoscopy and laparotomy (P 0.05). Conclusion compared with laparotomy, the volume of blood loss is less and the operative time is significantly longer than that of traditional laparotomy, which indicates that the operation under AEG microscope is more complicated. High operational skills are required.
【学位授予单位】：新疆医科大学
【学位级别】：硕士
【学位授予年份】：2015
【分类号】：R735

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