儿童幕上原始神经外胚层肿瘤的MRI诊断及病理对照研究

发布时间：2018-02-24 16:52

本文关键词： 神经外胚瘤原始儿童病理学磁共振成像　出处：《中国临床医学影像杂志》2017年02期 　论文类型：期刊论文

【摘要】：目的:探讨儿童幕上原始神经外胚层肿瘤(sPNET)的MRI表现特点。方法 :收集经手术及病理证实的20例sPNET,所有病例均行常规MRI平扫和增强扫描,并行DWI扫描。结果 :20例sPNET分别位于大脑半球的额、颞、顶、枕、岛叶及侧脑室内,14例为巨大囊实性肿瘤,4例以实性为主伴发小囊性变肿瘤,2例肿瘤体积小且以钙化为主。所有病例瘤周无水肿或水肿较轻,合并出血5例,3例术后复查沿蛛网膜下腔播散。MR平扫肿瘤呈混杂信号,肿瘤实性部分T_1WI呈等或稍低信号,T_2WI呈等或稍高信号,DWI呈高信号,ADC图呈低信号,囊变部分信号复杂。增强检查肿瘤实性部分呈中等或明显强化。结论:sPNET影像学表现有一定特征,尤其是DWI,这可能有助于肿瘤定性诊断,同时能够提供肿瘤浸润的范围、有无蛛网膜下腔种植转移,对疾病分期和制定治疗方案有重要价值。
[Abstract]:Objective: to investigate the MRI features of supratentorial primitive neuroectodermal neoplasms in children. Methods: 20 cases of supratentorial primitive neuroectodermal tumors proved by operation and pathology were collected. Results 20 cases of sPNET were located in the frontal, temporal, parietal, occipital, frontal, temporal, parietal, and occipital regions of the cerebral hemisphere. 14 cases of insular lobes and lateral ventricles were giant cystic solid tumors, 4 cases were solid tumors with small cystic neoplasms, 2 cases had small tumor size and mainly calcification. There was no edema or mild edema around the tumor in all cases. In 5 cases with hemorrhage, 3 cases showed mixed signal intensity along subarachnoid cavity spread. Mr plain scan showed mixed signal, and the solid part of tumor presented iso-or slightly low signal intensity on T _ 1WI. T2WI showed iso-or slightly high signal intensity and DWI showed high signal signal. The signal intensity of the cystic lesions is complex. The enhancement of the solid part of the tumor is moderate or obvious. Conclusion the imaging findings of SPNET have some characteristics, especially DWI, which may be helpful to the qualitative diagnosis of the tumor and provide the range of tumor infiltration. Subarachnoid subarachnoid implant metastasis is of great value to the stage of disease and the formulation of treatment plan.
【作者单位】：南京医科大学附属儿童医院放射科;南京医科大学第一附属医院放射科;
【分类号】：R739.41;R445.2

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