原发性肝癌精准肝切除与不规则性肝切除的对比研究

发布时间：2018-02-24 21:05

本文关键词： 原发性肝癌精准肝切除不规则性肝切除　出处：《实用医学杂志》2017年20期 　论文类型：期刊论文

【摘要】：目的探讨精准肝切除对早期肝癌根治性切除的应用价值。方法采用对比研究方法,收集2012年7月至2014年6月南方医院174例行肝癌根治性切除术肝癌患者的临床资料,将以精准肝切除术施行的设为精准组(118例),以Pringle法施行的设为传统组(56例)。比较分析患者术前基本资料,术中出血量、输血量,术后肝功能恢复情况、住院天数,术后1、2年无瘤生存率等。结果两组患者的性别、年龄、基础肝病、术前白蛋白、丙氨酸氨基转移酶、天门冬氨酸氨基转移酶、饮酒史、肝硬化等一般资料比较,差异无统计学意义(P0.05)。两组患者术中出血量、输血量、手术花费对比,其差异无统计学意义(P0.05)。精准组较传统组术后肝功能恢复更快,并发症发生率低,住院天数、引流管留置时间更短,差异具有统计学意义(P0.05)。术后1、2年无瘤生存率精准组为79.7%(94/118)、60.9%(46/118),传统组为50.0%(28/56)、46.4%(26/56),两组比较差异有统计学意义(χ~2=4.741,8.722,P0.05)。结论早期肝癌以精准肝切除术行根治性切除,患者术后恢复加快,并发症发生减少,具有更好的疗效,临床上可优先考虑该法。
[Abstract]:Objective to evaluate the value of accurate hepatectomy in early radical hepatectomy. Methods the clinical data of 174 patients undergoing radical hepatectomy in Southern Hospital from July 2012 to June 2014 were collected. The accurate hepatectomy group (n = 118) and the traditional group (n = 56) performed by Pringle method were divided into three groups: preoperative basic data, intraoperative bleeding volume, blood transfusion volume, postoperative liver function recovery, and hospitalization days. Results Sex, age, basic liver disease, preoperative albumin, alanine aminotransferase, aspartate aminotransferase, alcohol drinking history, liver cirrhosis and other general data were compared between the two groups. There was no significant difference between the two groups (P 0.05). There was no significant difference in intraoperative blood loss, blood transfusion and operation cost between the two groups. The recovery of liver function in the precision group was faster than that in the traditional group, and the incidence of complications was lower, and the hospitalization days were lower than those in the traditional group. The length of drainage tube indwelling was shorter, and the difference was statistically significant (P 0.05). The 1- and 2-year tumor-free survival rate of the accurate group was 79.7 / 118- 60.946 / 118g / 118g, and that of the traditional group was 50.028 / 566.46.40.The difference between the two groups was statistically significant (蠂 ~ 24.741 ~ 8.722p 0.05). Conclusion the early stage of liver cancer is resected by accurate hepatectomy, and the difference between the two groups is statistically significant (蠂 ~ (2) 4.741 + 8.722 / P ~ (0.05)). The postoperative recovery was accelerated, the complications were reduced, and the effect was better. This method can be given priority in clinical practice.
【作者单位】：南方医科大学南方医院肝胆外科;
【基金】：广州市协同创新重大专项(编号:201400000001-3)
【分类号】：R735.7

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