腹腔镜腹膜外前列腺癌根治术临床疗效分析

发布时间：2018-02-25 07:35

本文关键词： 前列腺癌前列腺癌根治术腹膜外途径并发症　出处：《中国医科大学学报》2017年01期 　论文类型：期刊论文

【摘要】：目的评价腹腔镜腹膜外前列腺癌根治术(ELRP)的临床疗效并总结手术经验。方法回顾性分析2010年1月至2015年6月我院同一术者完成的50例ELRP手术患者的临床资料。结果 50例均在腹腔镜下顺利完成手术,平均手术时间238.8min,平均手术出血量409.1 m L,术中或术后输血6例(12%);术后平均留置导尿时间23.7 d;术后平均住院15 d。术后恢复进食时间2~4 d,离床活动时间1~3 d。术后淋巴结阳性3例(6%),切缘阳性7例(14%)。出现手术相关并发症共9例(18%)。术后随访6~58个月,平均12.5个月。生化复发1例(2%),术后无瘤生存率达84%。至随访终点未出现尿失禁病例,尿控率达100%。结论 ELRP的临床应用安全有效,随着微创技术的发展,手术适应证越来越广泛,但对于高危前列腺癌患者术后的肿瘤学效果仍需大样本及长时间随访研究。
[Abstract]:Objective to evaluate the clinical effect of laparoscopic extraperitoneal prostatectomy for prostatic cancer and summarize the experience of the operation. Methods the clinical data of 50 cases of ELRP operation performed in our hospital from January 2010 to June 2015 were analyzed retrospectively. Results 50 cases were successfully operated under laparoscope. The mean operative time was 238.8 min, the average amount of operative bleeding was 409.1 mL, the blood transfusion was 12 cases during or after operation, the mean time of indwelling urethral catheterization after operation was 23.7 days, the average hospitalization time was 15 days, the recovery time of food was 24 days, the time of moving from bed was 1 and 3 days after operation. 3 cases were positive and 7 cases were positive in incisal margin, 9 cases had complications associated with operation. The follow-up was 6 ~ 58 months after operation. The mean time was 12. 5 months. One case of biochemical recurrence had a tumor free survival rate of 84. To the end of follow-up, there were no urinary incontinence cases, and the urinary control rate was 100. Conclusion the clinical application of ELRP is safe and effective. With the development of minimally invasive technique, the indication of operation is more and more extensive. However, a large sample and long-term follow-up study is needed for postoperative oncology in high-risk prostate cancer patients.
【作者单位】：大连医科大学附属第二医院泌尿外科;
【分类号】：R737.25

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