基于体素内不相干运动DWI在食管癌诊断中的应用价值

发布时间：2018-03-11 19:18

本文选题：食管癌　切入点：扩散加权成像　出处：《临床放射学杂志》2017年04期 　论文类型：期刊论文

【摘要】：目的探讨多b值双指数模型DWI对食管癌的诊断价值。方法 35例经病理证实的食管癌患者纳入研究,所有患者均行多b值DWI检查(11个b值:0、10、20、30、50、100、200、400、800、1200、1500 s/mm~2)。获得双指数模型参数:标准表观扩散系数(ADC_(st))、慢速表观扩散系数(ADC_(slow))、快速表观扩散系数(ADC_(fast))、快速扩散成分所占比例(F_(fast))。绘制ROC曲线,比较各参数对食管癌病变与正常食管管壁的诊断效能。结果病变组的ADC_(slow)、ADC_(fast)、ADC_(st)、F_(fast)值分别为(1.18±0.18)×10~(-3)mm~2/s、(10.63±4.87)×10~(-3)mm~2/s、(2.30±0.46)×10~(-3)mm~2/s、0.42±0.15;正常组的ADC_(slow)、ADC_(fast)、ADC_(st)、F_(fast)值分别为(1.24±0.25)×10~(-3)mm~2/s、(10.36±3.71)×10~(-3)mm~2/s、(2.88±0.57)×10~(-3)mm~2/s、0.59±0.12。两组间F_(fast)值差异具有统计学意义。ROC曲线分析发现F_(fast)值鉴别两者的最佳诊断界点为0.47,敏感性为88.1%,特异性为56.9%,曲线下面积为0.784。结论多b值双指数衰减模型能够有效评价食管癌血流灌注与扩散变化信息,F值对食管癌的诊断效能较高。
[Abstract]:Objective to study the diagnostic value of DWI in esophageal carcinoma with multiple b value and double index. Methods 35 patients with esophageal carcinoma confirmed by pathology were included in the study. All patients were examined with multi-b DWI (11 b: 01020 / 3050 / 100 / 200 / 400 / 800 / 1200 / 1500 s / mm / 2). The parameters of double exponential model were obtained: standard apparent diffusion coefficient, slow apparent apparent diffusion coefficient, rapid apparent diffusion coefficient, fast diffusion component, fast diffusion component, fast diffusion component, and ratio of fast diffusive components to ROC. Results the value of ADCD fast / ADCstastio Fasta in the normal group was 1.18 卤0.18 脳 10 ~ (-3) mm ~ (-2) / (10.63 卤4.87) 脳 10 ~ (-3) mm ~ (-2) / s ~ (-1) 脳 10 ~ (-1) 卤0.46) 脳 10 ~ (-3) mm ~ (-2) / s ~ (0.42 卤0.15) respectively. The ADCslow / ADCstS / ADCstastig / FFfast was found to be 1.24 卤0.25) -3mm ~ (3 脳 10 ~ (-1) 脳 10 ~ (-1) 脳 10 ~ (-1) 脳 10 ~ (-1) 脳 10 ~ (-1) 脳 10 ~ (-2) mm ~ (-1)). The best diagnostic cutoff point was 0.47, the sensitivity was 88.1, the specificity was 56.9, and the area under the curve was 0.784.Conclusion the multi-b double exponential attenuation model can effectively evaluate the diagnostic efficacy of the information of perfusion and diffusion in esophageal carcinoma.
【作者单位】：泰山医学院附属医院影像中心;
【分类号】：R445.2;R735.1

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