实时超声导航下解剖性肝段切除在原发性肝癌治疗中的应用及疗效分析

发布时间：2018-03-11 21:02

本文选题：癌　切入点：肝细胞　出处：《中国普通外科杂志》2017年01期 　论文类型：期刊论文

【摘要】：目的:探讨原发性肝细胞癌(肝癌)治疗中应用实时超声导航的解剖性肝段切除的疗效。方法:回顾2014年6月—2015年6月安徽医科大学附属安徽省立医院30例行实时超声导航下解剖性肝段切除的肝癌患者(观察组)与30例行非解剖性肝段切除的肝癌患者(对照组)临床资料,比较两组患者相关临床指标。结果:两组患者术前一般资料具有可比性。与对照组比较,观察组手术时间延长(153.5 min vs.128.5 min,P0.05),术中出血量无统计学差异(175.0 m L vs.200.00 m L,P0.05),但术中输血率降低(10.0%vs.36.7%,P0.05)、肝门阻断率降低(16.7%vs.40.0%,P0.05);两组并发症发生率无统计学差异(13.3%vs.33.3%,P0.05);观察组的1年复发率低于对照组(16.7%vs.43.3%,P0.05),1年存活率高于对照组(80.0%vs.53.3%,P0.05)。结论:实时超声导航下解剖性肝段切除的应用对减少肝癌患者术后肿瘤的复发、改善预后有着积极的作用。
[Abstract]:Objective: to investigate the effect of anatomical segmental resection with real-time ultrasound in the treatment of primary hepatocellular carcinoma (HCC). Methods: from June 2014 to June 2015, 30 cases of Anhui Provincial Hospital affiliated to Anhui Medical University were reviewed. The clinical data of liver cancer patients (observation group) and non-anatomical hepatectomy patients (control group) were observed. Results: the preoperative general data of the two groups were comparable. In the observation group, the operation time was prolonged 153.5 min / min P0.05, and there was no significant difference in the amount of blood loss during the operation. However, the blood transfusion rate decreased 10.0vs.36.7% P0.05, and the occlusion rate of hepatic porta decreased 16.7vs.40.010% P0.055.There was no significant difference in the incidence of complications between the two groups (13.3vs.33.3p0.05m); the 1-year recurrence in the observation group was higher than that in the control group (P 0.05), and the rate of hepatic portal occlusion was decreased by 16.7vs.40.050.The incidence of complications in the observation group was not significantly different from that in the control group (P 0.05). The rate was lower than that in the control group (16.7vs.43.3), and the 1-year survival rate was higher than that in the control group (80.0vs.53.3%). Conclusion: the application of anatomical segmentectomy under real-time ultrasound guidance can reduce the recurrence of liver cancer after operation. Improving prognosis has a positive effect.
【作者单位】：安徽医科大学附属省立医院肝脏外科/肝胆胰外科安徽省重点实验室;
【基金】：安徽省自然科学基金资助项目(1608085MH198)
【分类号】：R735.7

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