CT能谱成像在胃癌与高度侵袭危险性胃间质瘤鉴别诊断中的应用

发布时间：2018-03-12 13:43

本文选题：体层摄影术　切入点：X线计算机　出处：《临床放射学杂志》2017年06期 　论文类型：期刊论文

【摘要】：目的探讨CT能谱成像在胃癌与高度侵袭危险性胃间质瘤鉴别诊断中的应用价值。方法回顾性分析经手术病理证实并行CT能谱成像双期增强扫描的30例胃癌及24例高度侵袭危险性胃间质瘤患者的影像资料,通过GSI Viewer分析软件获得病灶能谱曲线,分别计算40~70、70~140、40~140 ke V各能量区间的能谱曲线斜率。同时测量病灶的碘浓度(IC)、水浓度(WC),并计算标准化后的碘浓度(NIC)(病灶碘浓度与同层腹主动脉碘浓度的比值)。结果采用独立样本t检验进行统计学分析,比较两组间的能谱参数差异。结果静脉期,胃癌组的IC(23.78±6.85)(100μg/mL)、NIC(0.54±0.15)均大于相应期相高度侵袭危险性胃间质瘤组(16.87±2.67)(100μg/m L)、(0.34±0.04)(P0.05),两组的WC差别无统计学意义(P0.05);静脉期胃癌组在40~70、70~140、40~140 ke V各能量区间的能谱曲线斜率(4.64±1.28、0.68±0.21、1.87±0.53)均大于相应期相胃间质瘤组(3.35±0.52、0.48±0.11、1.33±0.20)(P0.05)。动脉期胃癌组与高度侵袭危险性胃间质瘤组的IC、NIC、WC及各能量区间的能谱曲线斜率差异均无统计学意义(P0.05)。结论胃癌和高度侵袭危险性胃间质瘤具有不同的能谱成像参数,可以借助能谱参数对二者进行鉴别诊断。
[Abstract]:Objective to evaluate the value of CT energy dispersive imaging in the differential diagnosis of gastric cancer from highly invasive gastric stromal tumors. Methods 30 cases of gastric carcinoma and 24 cases of gastric carcinoma with dual-phase enhanced CT scan proved by surgery and pathology were analyzed retrospectively. Imaging data of patients with highly invasive gastric stromal tumors, The energy spectrum curves of the lesions were obtained by GSI Viewer software. The slope of the energy spectrum curve of each energy range of 4070 / 70 / 140 / 140 ~ 140ke V was calculated respectively. The iodine concentration of the lesion was measured, and the water concentration and the iodine concentration were calculated. The ratio of the iodine concentration of the lesion to the iodine concentration of the same layer of the abdominal aorta was calculated by using the method of measuring the ratio of the iodine concentration of the lesion to the iodine concentration of the same layer of the abdominal aorta. Independent sample t-test was used for statistical analysis. The differences of energy spectrum parameters between the two groups were compared. The IC(23.78 卤6.85 ~ 100 渭 g 路mL ~ (-1) Nic _ (0.54 卤0.15) in gastric cancer group was higher than that in the corresponding phase high risk gastric stromal tumor group (16.87 卤2.67 ~ 100 渭 g 路mL ~ (-1)), 0.34 卤0.04 (P _ (0.05)). There was no significant difference in WC between the two groups (P _ (0.05)), and the energy spectrum curve slope was 4.64 卤1.280.68 卤0.21 卤0.53 卤0.53 in the vein phase gastric cancer group. In stromal tumor group, there was no significant difference in ICNICWC and energy spectrum slope between arterial gastric cancer group and high invasive risk gastric stromal tumor group (P 0.05). Conclusion gastric carcinoma and highly invasive stromal tumor have different EDS imaging parameters. Energy spectrum parameters can be used to differentiate the two.
【作者单位】：郑州大学第一附属医院放射科;
【基金】：国家自然科学基金面上项目(编号:81271573)
【分类号】：R730.44;R735.2

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