微创McKeown食管癌切除术中喉返神经旁淋巴结清扫的可行性与安全性研究

发布时间：2018-03-13 03:09

本文选题：食管肿瘤　切入点：微创性　出处：《新疆医科大学》2017年硕士论文　论文类型：学位论文

【摘要】：目的:探讨微创McKeown食管癌切除术喉返神经旁淋巴结清扫的可行性、安全性。方法:回顾性分析新疆医科大学附属肿瘤医院行微创McKeown食管癌切除术的食管鳞癌患者163例,依术式的不同分为常规组63例、右侧喉返神经旁淋巴结清扫组(右侧组)53例、双侧喉返神经旁淋巴结清扫组(双侧组)47例。比较各组患者术后病理情况、手术时间、术中出血量、术后住院时长、淋巴结清扫数及肺炎、吻合口瘘、喉返神经损伤等并发症情况。病理情况包括肿瘤部位、病理分化程度、T分期以及病理分期。术后并发症随访时间至术后6个月。结果:常规组、右侧组、双侧组的肿瘤部位、病理分化程度、T分期以及病理分期差异均无统计学统计意义。常规组、右侧组、双侧组出血量呈逐渐下降趋势;双侧组总淋巴结和胸腔淋巴结清扫数高于右侧组及常规组(均P0.01);而其他各指标组间比较差异均无统计学意义。结论:微创McKeown食管癌切除术行双侧喉返神经旁淋巴结清扫具有较好的安全性及可行性。
[Abstract]:Objective: to investigate the feasibility and safety of minimally invasive McKeown resection of recurrent laryngeal lymph nodes. Methods: a retrospective analysis was made on 163 patients with esophageal squamous cell carcinoma undergoing minimally invasive McKeown resection of esophageal carcinoma in the Cancer Hospital affiliated to Xinjiang Medical University. According to the different operation methods, 63 cases were divided into routine group, right recurrent laryngeal nerve lymph node dissection group (right group, 53 cases), bilateral recurrent laryngeal nerve lymph node dissection group (bilateral group, 47 cases). Complications such as intraoperative bleeding, length of stay after operation, lymph node dissection and pneumonia, anastomotic fistula, injury of recurrent laryngeal nerve, etc. T stage and pathological stage. Postoperative complications were followed up to 6 months after operation. Results: tumor site in routine group, right group, bilateral group, and so on. There was no statistical difference in T stage and pathological stage of pathological differentiation. The amount of blood loss in routine group, right group and bilateral group was decreased gradually. The total lymph node and thoracic lymph node dissection in bilateral group was higher than that in right group and routine group (all P 0.01), but there was no significant difference between other groups. Conclusion: bilateral recurrent laryngeal nerve lymph nodes were performed by minimally invasive McKeown resection of esophageal carcinoma. Knot cleaning has good safety and feasibility.
【学位授予单位】：新疆医科大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R735.1

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