梅毒螺旋体感染与宫颈癌和卵巢癌的相关性研究

发布时间：2018-03-14 01:12

  本文选题：宫颈癌　切入点：卵巢癌　出处：《中华医院感染学杂志》2017年17期 　论文类型：期刊论文

【摘要】：目的探究在妇科恶性肿瘤患者中,宫颈癌和卵巢癌与梅毒螺旋体感染的相关性。方法选取2013年2月-2016年8月医院妇科住院治疗的宫颈癌患者269例和卵巢癌患者106例为研究对象,并选取1 000例普通患者作为对照,对宫颈癌组、卵巢癌组和普通患者组进行梅毒螺旋体感染检查,比较三组患者梅毒螺旋体感染率,对宫颈癌和卵巢癌患者按照术后病理学诊断进行分型,比较各主要类型患者的梅毒螺旋体感染率;比较宫颈癌组患者不同分期、不同年龄段、不同学历区间的梅毒螺旋体感染率。结果宫颈癌组患者感染梅毒螺旋体31例,感染率为11.5%,卵巢癌组患者感染梅毒螺旋体4例,感染率为3.8%,普通患者组感染梅毒螺旋体34例,感染率为3.4%,宫颈癌组与普通患者组梅毒螺旋体感染率比较差异有统计学意义(P0.05),而卵巢癌组与普通患者组梅毒螺旋体感染率比较差异无统计学意义;宫颈鳞状细胞癌患者感染率为12.6%,宫颈腺癌患者感染率为3.2%,腺鳞癌患者感染率为0,宫颈鳞状细胞癌患者梅毒螺旋体感染率与其他宫颈癌病理分型比较,差异有统计学意义(P0.05),浆液性囊腺癌患者感染率为4.1%,黏液性囊腺癌患者感染率为2.8%,子宫内膜样癌患者感染率为4.8%,卵巢癌3种病理分型患者梅毒螺旋体感染率比较差异无统计学意义;宫颈癌Ⅰ期患者感染率为16.2%,宫颈癌Ⅱ期患者感染率为6.3%,宫颈癌组不同分期感染率比较,差异有统计学意义(P0.05);30~39岁区间梅毒螺旋体感染率为18.5%,40~49岁区间感染率为24.6%,50~59岁区间感染率为5.6%,60岁区间感染率为2.0%,宫颈癌组不同年龄区间的感染率比较,差异有统计学意义(P0.05);高中学历以下患者感染率为16.2%,高中学历及以上患者感染率为5.8%,宫颈癌组不同学历区间的感染率比较,差异有统计学意义(P0.05)。结论宫颈癌患者有更大可能性感染梅毒螺旋体,卵巢癌患者与感染梅毒螺旋体无明显关系,且宫颈癌患者感染梅毒螺旋体与病理分型、病理分期、年龄和学历有关。
[Abstract]:Objective to investigate the correlation between cervical cancer and ovarian cancer and syphilis Treponema pallidum infection in gynecological malignant tumor patients. Methods 269 patients with cervical cancer and 106 patients with ovarian cancer who were hospitalized in gynecology from February 2013 to August 2016 were selected as subjects. The infection rate of Treponema pallidum in cervical cancer group, ovarian cancer group and general patient group was compared with that of cervical cancer group, ovarian cancer group and normal patient group. The patients with cervical cancer and ovarian cancer were classified according to postoperative pathological diagnosis to compare the infection rate of Treponema pallidum in each major type of patients, and different stages and ages of patients with cervical cancer were compared. Results there were 31 cases of Treponema pallidum infection in cervical cancer group, 4 cases in ovarian cancer group, and 3.8% in ovarian cancer group, and 34 cases were infected with Treponema pallidum in normal group. The infection rate of Treponema pallidum in cervical cancer group and normal patient group was 3.4. there was a significant difference in the infection rate of Treponema pallidum between cervical cancer group and normal patient group, but there was no significant difference between ovarian cancer group and normal patient group. The infection rate of cervical squamous cell carcinoma, adenocarcinoma and adenosquamous carcinoma was 12.6, 3.2 and 0 respectively. The infection rate of Treponema pallidum in patients with squamous cell carcinoma of cervix was higher than that in other cervical cancer. The infection rate of serous cystadenocarcinoma was 4.1, that of mucinous cystadenocarcinoma was 2.8, that of endometrioid carcinoma was 4.8. The infection rate of Treponema pallidum was lower in three types of ovarian cancer. There was no statistical significance. The infection rate of patients with stage I cervical cancer was 16.2and the infection rate of patients with stage 鈪，

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