妊娠晚期HPV感染孕产妇阴道炎发生率及妊娠结局的影响分析

发布时间：2018-03-16 17:47

本文选题：人乳头瘤病毒　切入点：妊娠晚期　出处：《中华医院感染学杂志》2017年23期 　论文类型：期刊论文

【摘要】：目的研究分析妊娠晚期人乳头瘤病毒(HPV)感染孕产妇阴道炎发生率及对妊娠结局的影响。方法选择2015年5月-2016年5月期间医院接诊的妊娠晚期HPV感染孕产妇120例为试验组,选取同期HPV检测结果为阴性的正常孕妇120名为对照组,孕周28~32周,取阴道、宫颈分泌物进行检测,并追踪两组孕产妇妊娠结局和新生儿结局。结果试验组孕产妇PH值4.5、细菌性阴道炎检出率为60.83%、40.00%,高于对照组33.33%、21.67%,差异有统计学意义(P0.05);两组孕产妇自然分娩、剖宫产率比较,差异无统计学意义;两组孕产妇早产、胎膜早破、产后出血、产褥感染、胎儿生长受限等妊娠结局比较,差异无统计学意义;试验组中自然分娩、剖宫产分娩的新生儿脐血、羊水、胎盘、咽部或外阴分泌物中HPV阳性检出率比较,差异无统计学意义。结论妊娠晚期孕产妇HPV感染风险高,与阴道内酸性环境破坏有关,易导致细菌性阴道炎发生,妊娠合并HPV感染对妊娠结局、新生儿影响并不大,不同分娩方式下新生儿HPV感染无明显差异,但仍需采取相关措施进行治疗,避免新生儿感染,改善母婴预后。
[Abstract]:Objective to study the advanced human papilloma virus (HPV) infection among pregnant women in pregnancy vaginitis prevalence and effects on pregnancy outcomes. Methods from May 2015 May -2016 during late pregnancy hospital admissions of 120 cases of HPV infected pregnant women were selected as the experimental group, HPV test results were negative in 120 normal pregnant women as control group, 28~32 weeks of gestation week, vaginal, cervical secretions were detected, and follow-up of two groups of maternal pregnancy outcomes and neonatal outcomes. The results of the experimental group in pH 4.5, bacterial vaginosis detection rate was 60.83%, 40%, 21.67%, 33.33% higher than the control group, the difference was statistically significant (P0.05); the two groups of maternal natural childbirth, compare cesarean section rate. There was no significant difference between two groups of pregnant women; premature birth, premature rupture of membranes, postpartum hemorrhage, puerperal infection, fetal growth restriction and pregnancy outcome in comparison, no statistically significant difference in self test group; Natural childbirth, cesarean delivery in umbilical cord blood, amniotic fluid, placenta, throat or genital secretions in HPV positive rate, the difference was not statistically significant. Conclusion HPV infection during late pregnancy. The high risk associated with the acidic vaginal environment damage, easily lead to bacterial vaginal inflammation and HPV infection in pregnancy on pregnancy outcome the newborn, did not affect the different delivery modes of neonatal HPV infection had no obvious difference, but still need to take measures for treatment, avoid neonatal infection, improve the prognosis of the patients.

【作者单位】：丽水市中心医院妇产科;
【基金】：浙江省卫生厅基金资助项目(2013KYB300)
【分类号】：R711.31;R737.33

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