36例胃神经内分泌肿瘤临床、内镜和病理分析

发布时间：2018-03-17 11:45

本文选题：胃神经内分泌肿瘤　切入点：临床表现　出处：《中国医学科学院学报》2017年02期 　论文类型：期刊论文

【摘要】：目的探讨胃神经内分泌肿瘤(GNENs)的临床特征,以提高临床医师对本病的认识。方法收集2005年10月至2015年10月北京协和医院收治的36例GNENs,对其人口学特征、主要临床表现、内镜下表现、病理特征及治疗情况进行回顾性分析。结果 36例患者平均年龄(55.8±11.1)岁,男女比例0.89∶1。临床表现多种多样,腹痛的发生率高达42.9%。63.9%的病变分布于胃体部。内镜下病变可表现为息肉样隆起、溃疡性病变、黏膜凹陷。以息肉样隆起最为多见,其中73.9%为单发病变,平均直径小于10 mm。病理分级包括G1~G3级,以G1级居多(55.6%)。65.2%于胃体行活检的患者病理证实存在胃体黏膜萎缩或肠化。治疗方案主要包括内镜和手术根治。结论 GNENs缺乏特异性临床表现,病变以胃体分布居多,在内镜下多表现为息肉样隆起。对于合并萎缩性胃炎,尤其胃体萎缩的息肉样病变,应警惕GNENs的可能性。
[Abstract]:Objective to investigate the clinical features of GNENs in patients with gastric neuroendocrine neoplasms (GNENNs) and to improve the clinical understanding of GNENs. Methods from October 2005 to October 2015, 36 cases of GNENs in Beijing Union Hospital were collected and their demographic characteristics and main clinical manifestations were analyzed. Results the average age of 36 patients was 55.8 卤11.1 years old, and the ratio of male to female was 0.89: 1.The clinical manifestations were varied. The incidence of abdominal pain is as high as 42.9%. 63.9% of the lesions are located in the stomach. Endoscopic lesions can be seen as polypoid bulge, ulcerative lesion, mucosal depression. Polypoid eminence is the most common, of which 73.9% are single lesions. The mean diameter is less than 10 mm. the pathological grading includes G1 and G3. Pathological evidence of gastric mucosal atrophy or intestinal metaplasia was found in 55.6% of patients with G _ 1 grade and 55.6% of whom underwent gastric body biopsy. The main treatment options included endoscopy and radical surgery. Conclusion GNENs has no specific clinical manifestations, and the gastric body is the most of the lesions. Polypoid eminence is more common in endoscopy. GNENs should be warned of in cases of atrophic gastritis, especially in cases with atrophic gastritis, especially in cases of atrophic gastritis.
【作者单位】：中国医学科学院北京协和医学院北京协和医院消化内科;
【分类号】：R735.2

【相似文献】