我国1996-2015年间肝癌经济负担研究系统评价

发布时间：2018-03-17 21:24

本文选题：肝肿瘤　切入点：患病代价　出处：《中华疾病控制杂志》2017年08期 　论文类型：期刊论文

【摘要】：目的整合我国肝癌经济负担证据,为今后研究提供基线数据和方法参考。方法系统检索Pub Med、中国知网和万方数据库1996-2015年间发表文献,描述纳入研究基本特征并分析经济负担结果,费用贴现至2013年值,采用美国卫生保健质量和研究机构(agency for health care research and quality,AHRQ)推荐的量表开展质量评价。结果最终纳入32篇文献。2篇基于人群的研究,报道的经济负担分别为37.8亿元(省级,直接和间接)和6.0亿元(市级,间接)。30篇基于个体的研究均报道了直接医疗费用,例均费用(21篇)年度中位数为11 663元(3 500~70 567元),次均费用(9篇)年度中位数为19 202元(7 005~41 118元),日均费用(13篇)年度中位数为865元(409~1 275元);20年间三种指标费用均呈缓慢上升趋势;细化构成药品费居多(约56.6%);5篇基于个体的研究报道了间接费用,中位数为73 440元(35 815~166 967元)。纳入研究质量一般。结论肝癌在我国人群层面经济负担研究有限。不同地区的肝癌经济负担研究力度与其疾病负担不相匹配。例均费用数据报道较多,但结果解释应谨慎。此外,肝癌所致间接经济负担不容忽视。
[Abstract]:Objective to integrate the evidence of the economic burden of liver cancer in China, and to provide baseline data and methodological references for future research. Methods Pub Med, China knowledge Network and Wanfang Database were searched systematically from 1996 to 2015. Description includes the basic characteristics of the study and analyses the results of economic burden. The cost is discounted to 2013. The quality evaluation was carried out by using the scale recommended by for health care research and quality Agency. Results 32 articles were included in this study. The economic burden of the report was 3.78 billion yuan (provincial level). Both direct and indirect) and 600 million yuan (municipal, indirect and 30 individual based studies) all reported direct medical costs, The median annual average cost per case is $11,663 / 3 500 / $70,567, the average annual average cost is $19,202 / 7 005 / 41 / 118, and the daily average cost is 13) the median annual median is $865 / $409/ $1,275 / 20 / 20. A slow upward trend; The breakdown of the composition of drug costs (about 56. 6%) reported indirect costs in 5 individual-based studies. The median value was 73 440 yuan / 35 815 / 166 / 967 yuan. Conclusion the study on the economic burden of liver cancer at the population level in China is limited. The study on the economic burden of liver cancer in different areas does not match its disease burden. There are more reports with data, But the results should be interpreted with caution. In addition, the indirect economic burden caused by liver cancer should not be ignored.
【作者单位】：广西医科大学公共卫生学院劳动卫生与环境卫生教研室;国家癌症中心/中国医学科学院北京协和医学院肿瘤医院城市癌症早诊早治项目办公室;徐州市疾病预防控制中心慢性非传染性疾病防治科;国家癌症中心/中国医学科学院北京协和医学院肿瘤医院免疫学研究室;国家癌症中心/中国医学科学院北京协和医学院肿瘤医院肝胆外科;
【基金】：国家自然科学基金(81402740) 教育部高等学校博士学科点专项科研基金(20131106120014) “十三五”传染病国家科技重大专项课题(2017ZX10201201-008-002) 国家重大公共卫生服务项目城市癌症早诊早治项目(2012年)
【分类号】：R735.7

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