支气管镜介入治疗原发性气道良性肿瘤18例临床分析

发布时间：2018-03-18 12:26

本文选题：气管镜　切入点：介入治疗　出处：《浙江大学》2017年硕士论文　论文类型：学位论文

【摘要】：目的:探讨原发性气道良性肿瘤患者的临床特点及诊断方法,以及电子支气管镜下介入治疗的临床疗效。资料与方法:回顾分析浙江大学医学院邵逸夫医院2009年2月至2015年7月收治的18例原发性气道良性肿瘤患者的临床表现、影像学资料、支气管镜下表现、病理类型及支气管镜下介入治疗方法及转归。结果:18例患者中男10例,女8例,病程在1个月～72个月,18例均有咳嗽症状及不同程度的呼吸困难,其中咯血3例,多数被误诊为支气管哮喘或慢性支气管炎;病理类型包括:错构瘤6例,多形性腺瘤1例,脂肪瘤3例,平滑肌瘤2例,炎性息肉1例,血管球瘤3例,炎性假瘤1例,异物性肉芽肿1例。全部患者均在局麻下进行气管镜下介入治疗手术,根据患者基本身体状况,肿瘤部位,肿瘤形态及肿瘤血供等特征,分别采取高频电圈套、氩等离子体凝切术(APC)以及冷冻治疗。所有病例经治疗后(支)气管腔内肿瘤均基本切除,狭窄气道恢复正常。其中16例患者一次性手术清除病灶,2例患者因肿瘤体积较大,分2次手术。术后无严重并发症,随访发现1例炎性息肉术后32周复发,1例多形性腺瘤术后20个月复发。结论:对于原发性气道良性肿瘤,在局麻下行支气管镜下介入治疗,不仅创伤较小,临床并发症也较少,不仅患者能耐受,而且疗效确切。
[Abstract]:Objective: to investigate the clinical features and diagnostic methods of primary benign airway tumors. Data and methods: the clinical manifestations of 18 patients with primary airway benign tumor admitted from February 2009 to July 2015 in run run Shaw Hospital of Zhejiang University Medical College were retrospectively analyzed. Results among 18 cases, 10 cases were male and 8 cases were female, 18 cases had cough symptom and dyspnea in different degree, the course of disease was from 1 month to 72 months. The pathological types of hemoptysis were hamartoma in 6 cases, pleomorphic adenoma in 1 case, lipoma in 3 cases, leiomyoma in 2 cases, inflammatory polyp in 1 case and angioblastoma in 3 cases. One case of inflammatory pseudotumor and one case of foreign body granuloma. All patients were treated with intratracheal interventional therapy under local anesthesia. According to the characteristics of patients' basic body condition, tumor location, tumor shape and tumor blood supply, high frequency electric trap was used respectively. Argon plasma coagulation (APC) and cryotherapy. After treatment, the tumor in trachea was basically resected and the narrow airway returned to normal in all cases. There were no serious complications after operation. 1 case of inflammatory polyp recurred 32 weeks after operation and 1 case of pleomorphic adenoma recurred 20 months after operation. Conclusion: for primary benign tumor of airway, interventional treatment under bronchoscope under local anesthesia is performed. Not only the trauma is small, the clinical complication is also less, not only the patient can tolerate, and the curative effect is definite.
【学位授予单位】：浙江大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R734

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