大肠癌住院患者生存质量调查及其影响因素分析

发布时间：2018-03-23 06:19

本文选题：大肠癌患者　切入点：生存质量　出处：《华北理工大学》2015年硕士论文　论文类型：学位论文

【摘要】：目的了解大肠癌患者生存质量的现状;分析大肠癌患者生存质量的影响因素。方法于2013年10月~2014年10月对河北联合大学附属医院及唐山市人民医院确诊住院的大肠癌患者248名进行了问卷调查,包括大肠癌患者的一般人口学特征的调查表(包括年龄、性别、婚且、职业、经济状况、医保等情况)、癌症患者生存质量量表、微型营养评估表(MNA)、日常生活能力量表(ADL)、医院焦虑抑郁量表(HAD)、社会支持评定量表(SSRS)、家庭功能评估表。所有数据采用Exce l软件输入建立数据库,使用SPSS17.0统计软件进行统计分析。结果1大肠癌患者生存质量现状:大肠癌患者生存质量评分:躯体功能(34.09±11.30)分,心理功能(30.29±11.59)分,症状/副作用(31.42±9.74)分,社会功能(28.84±8.84)分,生存质量总评分(124.69±31.95)分。2大肠癌患者生存质量的单因素分析:①躯体功能在居住地、婚问便是否正常、进食是否规律、有无腹痛、疾病转移、造瘘、化疗、化疗次数、手术后时间、ADL、个人收入、医疗费用支付方式、焦虑状态、社会功能、营养均有统计学意义(P0.05);②心理功能在是否饮酒、大便是否正常、进食是否规律、有无腹痛、有无腹胀、恶性肿瘤是否转移、化疗时是否恶心、营养状况、是否化疗、化疗次数、ADL、社会功能差异均有统计学意义(P0.05);③症状/副作用在居住地、职业、是否饮酒、腹痛、腹胀、恶性肿瘤是否转移、化疗时是否恶心、营养、造瘘、化疗次数、ADL、个人月收入、医疗费用支付方式、焦虑状态、社会功能差异均有统计学意义(P0.05)。④社会功能在居住地、职业、是否吸烟、大便是否正常、进食是否规律、恶性肿瘤是否转移、化疗次数、ADL、个人月收入、营养、家庭收入、医疗总费用、医疗费用支付方式、焦虑状态、抑郁状态、家庭功能及社会功能差异均有统计学意义(P0.05)。⑤生存质量总分在居住地、职业、是否饮酒、大便是否正常、进食是否规律、腹痛、腹胀、恶性肿瘤是否转移、化疗时是否恶心、营养、是否造瘘、是否化疗、化疗次数、ADL、个人月收入、医疗费用自付方式、焦虑状态、抑郁状态、家庭功能及社会功能差异均有统计学意义(P0.05)。3大肠癌患者生存质量的多因素分析:①躯体功能的影响因素有:化疗次数、ADL评分、焦虑状态、抑郁状态、是否饮酒;②心理功能维度的影响因素有:恶性肿瘤是否转移、大便是否正常、ADL评分、焦虑状态、抑郁状态、营养;③症状/副作用维度的影响因素有:是否饮酒、化疗时是否恶心、抑郁状态、ADL评分、营养状态;④社会功能维度的影响因素有:恶性肿瘤是否转移、大便形态、医疗总费用、抑郁状态、营养状态;⑤生存质量总评分的影响因素有:恶性肿瘤是否转移、是否饮酒、腹胀、化疗时是否恶性、焦虑状态、抑郁状态、ADL评分、营养状态。结论1大肠癌患者的生存质量总评分(124.69±31.95)分;2多因素分析显示:化疗次数、ADL评分、焦虑状态、抑郁状态、是否饮酒是大肠癌患者生存质量躯体功能维度的影响因素;恶性肿瘤是否转移、大便是否正常、ADL评分、焦虑状态、抑郁状态、营养是大肠癌患者生存质量心理功能维度的影响因素;是否饮酒、化疗时是否恶心、抑郁状态、ADL评分、营养状态是大肠癌患者生存质量症状/副作用维度的影响因素;恶性肿瘤是否转移、大便形态、医疗总费用、抑郁状态、营养状态是大肠癌患者生存质量社会功能维度的影响因素;恶性肿瘤是否转移、是否饮酒、腹胀、化疗时恶心程度、焦虑状态、抑郁状态、ADL评分、营养状态是大肠癌患者生存质量总评分的影响因素。
[Abstract]:Objective to understand the status of quality of life of patients with colorectal cancer; analysis of factors affecting the quality of life of patients with colorectal cancer. Methods from October 2013 to October ~2014 colorectal cancer patients diagnosed in Hospital Affiliated Hospital of Hebei United University and Tangshan City people's Hospital of 248 questionnaires, including the demographic characteristics of patients with colorectal cancer (including age, questionnaire gender, marriage and occupation, economic status, health insurance, etc.), the cancer patient quality of life scale, mini nutritional assessment (MNA), activity of daily living scale (ADL), hospital anxiety and Depression Scale (HAD), social support rating scale (SSRS), the family function scale. All data the input database using Exce l software and SPSS17.0 statistical software for statistical analysis. Results of the 1 colorectal cancer patients quality of life: the quality of life of patients with colorectal cancer: the scores of physical function (34.09 + 11.30), psychological The function of (30.29 + 11.59) points, symptoms / side effects (31.42 + 9.74), social function (28.84 + 8.84) points, the total score of quality of life (124.69 + 31.95) single factor analysis divided the life quality of patients with.2 colorectal cancer: physical function in place of residence, marriage will ask whether it is normal, whether eating there are no rules, abdominal pain, fistula, metastatic disease, chemotherapy, chemotherapy times, surgery time, ADL, personal income, payment of medical expenses, the state of anxiety, social function, nutrition had statistical significance (P0.05); the psychological function in drinking, the stool is normal, whether eating rules, there is no pain there is no abdominal distension, malignant tumor, metastasis, chemotherapy or nausea, nutritional status, chemotherapy, chemotherapy times, ADL, social function, the differences were statistically significant (P0.05); the symptoms / side effects in the place of residence, occupation, drinking, abdominal pain, abdominal distension, malignant tumor metastasis, chemotherapy is No nausea, nutrition, fistula, number of chemotherapy, ADL, personal income, payment of medical expenses, anxiety, social function, the differences were statistically significant (P0.05). The social function of residence, occupation, smoking, eating stool is normal, whether the law, malignant tumor metastasis, number of chemotherapy, ADL. Personal income, nutrition, family income, total medical expenses, payment of medical expenses, the state of anxiety, depression, family function and social function of the differences were statistically significant (P0.05). The total score of quality of life in the place of residence, occupation, drinking, eating stool is normal, whether the law, abdominal pain, abdominal distension, malignant tumor transfer, whether chemotherapy nausea, nutrition, whether fistula, chemotherapy, chemotherapy cycles, ADL, personal monthly income, medical expenses paid, the state of anxiety, depression, family function and social function were statistically differences Statistically significant (P0.05) multivariate analysis of the quality of life of patients with.3 colorectal cancer: factors affecting the physical function are: the number of chemotherapy, ADL score, anxiety, depression, alcohol consumption; influence factor of psychological function: malignant tumor metastasis, the stool is normal, ADL score, anxiety third, depression, nutrition; symptoms / side effects of the dimensions of the factors are: whether drinking, whether chemotherapy nausea, depression, ADL score, nutritional status; influencing factors and social function dimensions are: malignant tumor metastasis, stool form, total medical cost, depression, nutritional status; influencing factors the total score of quality of life are: malignant tumor metastasis, whether drinking, abdominal distension, chemotherapy is malignant, anxiety, depression, ADL score and nutritional status. The total score of quality of life of patients with colorectal cancer 1 (124.69 + 31.95) points; More than 2 factor analysis showed that the number of chemotherapy, ADL score, anxiety, depression, alcohol consumption are the factors influencing the quality of life of patients with colorectal cancer in the body function dimension; malignant tumor metastasis, stool is normal, ADL score, anxiety, depression, nutrition is the factors affecting the quality of life of patients with colorectal cancer psychological function dimension whether drinking, whether chemotherapy; nausea, depression, ADL score and nutritional status are influencing factors of quality of life of patients with colorectal cancer symptoms / side effects of dimension; malignant tumor metastasis, stool form, total medical cost, depression, nutritional status are the factors influencing the quality of life of patients with colorectal cancer and social function dimensions; malignant tumor metastasis is drinking, abdominal distension, chemotherapy nausea, anxiety, depression, ADL score and nutritional status are influencing factors of colorectal cancer patients with the total score of quality of life.

【学位授予单位】：华北理工大学
【学位级别】：硕士
【学位授予年份】：2015
【分类号】：R735.34

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