能谱CT在乳腺癌诊断中的初步应用

发布时间：2018-03-24 01:01

本文选题：乳腺肿瘤　切入点：体层摄影术　出处：《中国医学影像学杂志》2017年11期

【摘要】：目的探讨能谱CT在乳腺癌评估中的应用价值,为临床提供影像学辅助信息。资料与方法回顾性分析2016年5月-2017年2月兰州总医院经手术病理证实并行术前能谱CT双期增强扫描的乳腺癌患者12例,其中6例伴有淋巴结转移。以对侧正常腺体为对照,测量双期乳腺癌病灶及对侧正常腺体40~140 ke V下的平均CT值、能谱曲线斜率、碘(水)浓度及相对碘浓度。绘制原发灶及转移性淋巴结的能谱曲线、直方图及散点图。以12例胸部常规CT双期增强扫描的女性患者为对照进行辐射剂量对比评估,评估参数包括CT容积剂量指数、剂量长度乘积、有效辐射剂量。结果乳腺癌动、静脉期的各项能谱参数均明显高于正常腺体,差异有统计学意义(P0.05)。能谱CT胸部双期增强扫描的平均有效辐射剂量明显低于常规CT,差异有统计学意义(P0.05)。6例伴淋巴结转移的乳腺癌,原发灶与转移性淋巴结的能谱曲线、直方图及散点图均表现为在静脉期一致性较高。结论乳腺癌能谱参数的特征性表现有利于病变的进一步诊断。原发灶与转移淋巴结在能谱曲线、直方图及散点图等方面的一致性有助于淋巴结的定性诊断。能谱CT胸部双期增强扫描具有较低的辐射剂量,弥补了传统CT因辐射剂量问题在乳腺病变定性诊断方面的应用局限。因此,能谱CT在诊断乳腺癌方面具有一定的应用价值。
[Abstract]:Objective to evaluate the value of energy dispersive CT in the evaluation of breast cancer. Data and methods 12 patients with breast cancer confirmed by surgery and pathology in Lanzhou General Hospital from May 2016 to February 2017 were examined by dual-phase enhanced scanning with energy dispersive CT. In 6 cases with lymph node metastasis, the mean CT value and the slope of the energy spectrum curve were measured under 40140keV of the lesion and the contralateral normal gland in the contralateral normal gland as control. Iodine (water) concentration and relative iodine concentration. Energy spectrum curve, histogram and scattered plot of primary focus and metastatic lymph nodes were drawn. The evaluation parameters included CT volumetric dose index, dose length product, effective radiation dose. Results the energy spectrum parameters of breast cancer in arteriovenous phase were significantly higher than those in normal gland. The average effective radiation dose of dual phase enhanced chest CT scan was significantly lower than that of conventional CT.There was a statistically significant difference in the energy spectrum curve between primary focus and metastatic lymph node in 6 cases of breast cancer with lymph node metastasis. Histogram and scatter plot showed high consistency in venous phase. Conclusion the characteristic manifestation of energy spectrum parameters of breast cancer is helpful for the further diagnosis of breast cancer. The consistency of histogram and scatter plot is helpful for the qualitative diagnosis of lymph nodes. It makes up for the limitation of traditional CT in the qualitative diagnosis of breast lesions due to radiation dose. Therefore, energy dispersive CT has certain application value in the diagnosis of breast cancer.
【作者单位】：兰州总医院影像诊断科;
【基金】：甘肃省自然科学基金(1606RJZA160)
【分类号】：R730.44;R737.9

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