血管内皮生长因子及其受体与卵巢癌相关性的研究进展
发布时间:2018-04-07 18:32
本文选题:血管内皮生长因子 切入点:受体 出处:《中国老年学杂志》2017年02期
【摘要】:正卵巢癌早期往往不易诊断,约75%是在卵巢癌晚期及发生转移遍布腹膜、肝脏的实质或胸膜后才被确诊~(〔1〕)。尽管目前卵巢癌的治疗手段有所提高,但卵巢癌Ⅲ、Ⅳ期患者总体5年生存率分别为36%和17%~(〔2〕)。血管内皮生长因子(VEGF)为特异的内皮细胞有丝分裂素,通过其特异性受体(VEGFR)介导,在卵巢癌的发生、发展中发挥了举足轻重的作用,最终导致恶性腹水的产生。卵巢癌发生、发展机制分子水平的鉴定,为卵
[Abstract]:Early diagnosis of positive ovarian cancer is often difficult, about 75% of the ovarian cancer and metastasis occurred throughout the peritoneum, liver parenchyma or pleura was only diagnosed after the diagnosis.Although the current treatment of ovarian cancer has been improved, the overall 5-year survival rate of patients with stage 鈪,
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