2127例大肠癌临床发病特点的回顾性分析
发布时间:2018-04-09 23:27
本文选题:大肠癌 切入点:肠镜 出处:《肿瘤防治研究》2017年12期
【摘要】:目的探讨遵义医学院附属医院内镜中心近10年来检出的大肠癌发病情况、临床表现、内镜及病理特点,进一步阐明本地区大肠癌流行病学特征和临床特点。方法以我院2007—2016年来所有接受结肠镜检查的患者为研究对象,对大肠癌患病率、大肠癌患者性别、年龄、肿瘤部位、病理类型等进行回顾性分析与总结。结果 10年间共行大肠镜检查51 732例,检出大肠癌2 127例,占受检总数4.11%。2 127例大肠癌中,男1 267例、女860例。发病高峰年龄段在50~79岁之间,尤其是60~69岁之间;结肠癌714例、直肠癌1 413例;病理分类以腺癌为主,尤其以高分化腺癌为主,与性别无明显差异,但印戒细胞癌女性明显多于男性,差异有统计学意义(P0.05)。结论贵州省北部地区的大肠癌发病近年来呈逐渐上升趋势,男性发病明显多于女性,直肠癌是结肠癌发病的两倍左右,病理类型上女性大肠癌患者要注意印戒细胞癌的发生。因此,预防上重点对高危人群进行大肠癌普查、直肠指诊和结肠镜检查,可以有效地提高大肠癌的早诊早治率。
[Abstract]:Objective to investigate the incidence, clinical manifestations, endoscopic and pathological features of colorectal cancer in the endoscopic center of affiliated hospital of Zunyi Medical College in recent 10 years, and to further elucidate the epidemiological and clinical characteristics of colorectal cancer in this area.Methods all the patients underwent colonoscopy in our hospital from 2007 to 2016 were studied. The prevalence of colorectal cancer, sex, age, tumor location and pathological type of colorectal cancer patients were retrospectively analyzed and summarized.Results A total of 51,732 cases of colorectal cancer were examined during the past 10 years, 2127 cases of colorectal cancer were detected, accounting for 4.11.2 127 cases of colorectal cancer, among them 1 267 cases were males and 860 cases were females.The peak age of onset was between 50 to 79 years old, especially between 60 and 69 years, 714 cases of colon cancer and 1 413 cases of rectal cancer.However, the number of signet ring cell carcinoma in female was significantly higher than that in male, and the difference was statistically significant (P 0.05).Conclusion the incidence of colorectal cancer in the northern part of Guizhou Province is increasing gradually in recent years. The incidence of male colorectal cancer is more than that of female, and the incidence of rectal cancer is about twice as high as that of colon cancer. The pathological type of female colorectal cancer patients should pay attention to the occurrence of signet ring cell carcinoma.Therefore, the early diagnosis and treatment rate of colorectal cancer can be improved effectively by means of colorectal cancer screening, digital rectal examination and colonoscopy.
【作者单位】: 遵义医学院附属医院消化内科;
【分类号】:R735.34
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