原发性肝癌TACE治疗研究现状

发布时间：2018-04-17 18:37

本文选题：肝癌 + 介入治疗　；参考：《遵义医学院》2017年硕士论文

【摘要】：原发性肝癌是世界上最常见的恶性肿瘤之一,占恶性肿瘤发病率的第六位,在癌症相关死亡率中排名第三。我国是乙型肝炎患者、携带者最多的国家之一,85%-90%的肝癌是在肝炎后肝硬化的基础上发生的,每年肝癌新发病例占全球50%以上,其死亡率仅次于肺癌位居第二位,在某些农村高发地区甚至跃居第一位。外科手术被认为是最佳治疗方案。但是,肝癌起病较隐匿、发展迅速,临床确诊时多属于中、晚期,且由于肝癌患者常伴有肝功能储备差、肝内转移及血管侵犯而失去外科手术治疗机会,此时常需要联合其他治疗。自1978年经导管肝动脉化疗栓塞(TACE)提出以来,该技术得到广泛运用,随着巴塞罗那肝癌协作组分期法的提出,更确立了TACE在中期肝癌的主流治疗地位。研究证实肝癌TACE治疗能有效提高患者生活质量及生存期。随着目前多模式的介入治疗在临床实践中不断出现,介入治疗特别是TACE在肝癌治疗中取得了一定进步,本文就肝癌TACE治疗研究现状进行综述如下。以期为肝癌在临床治疗方法的选择上起到一定的启发作用。
[Abstract]:Primary liver cancer is one of the most common malignant tumors in the world.China is a patient with hepatitis B, and 85% to 90% of liver cancer occurs on the basis of posthepatitic cirrhosis in one of the countries with the most carriers. Each year, new cases of liver cancer account for more than 50% of the world, and the mortality rate is second only to lung cancer.In some rural areas with high incidence, they even rank first.Surgery is considered the best treatment.However, the onset of liver cancer is concealed, and it develops rapidly. The clinical diagnosis is usually of middle and late stage, and the opportunity of surgical treatment is lost due to poor liver function reserve, intrahepatic metastasis and vascular invasion in patients with liver cancer.Other treatments are often needed at this time.Since TACE was put forward in 1978, this technique has been widely used. With the development of Barcelona cooperative group staging method for liver cancer, the mainstream status of TACE in the treatment of middle stage liver cancer has been established.It has been proved that TACE therapy can effectively improve the quality of life and survival time of patients with liver cancer.With the emergence of multi-mode interventional therapy in clinical practice, interventional therapy, especially TACE, has made some progress in the treatment of liver cancer.In order to play a certain role in the choice of clinical treatment for liver cancer.
【学位授予单位】：遵义医学院
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R735.7

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