双源CT容积测定评估肺癌患者肺功能的应用

发布时间：2018-05-12 22:19

本文选题：肺癌 + CT后处理技术　；参考：《中国现代医学杂志》2017年27期

【摘要】：目的应用双源CT后处理技术计算肺癌患者吸气末和呼气末容量参数,并与传统肺功能检查(PFT)参数相对比,探讨其评价肺功能中的意义。方法对32例肺癌患者,术前1周内行肺功能检查及深吸气相和深呼气胸部CT扫描,采用SIEMENS工作站Volume及Pulmo模块软件进行扫描后处理,得到吸气末和呼气末的肺容积。将CT后处理数据与肺功能检查主要数据相比较,采用Pearson分析相关性。结果肺癌患者术前吸气相和呼气相全肺容积差值(Vin-Vex)与肺总量(TLC)、第1秒用力肺活量的实测值FEV1、用力肺活量实际值(FVC)呈正相关(r=0.80、0.91和0.82,均P0.05),CT扫描获得的吸气相容积值(Vin)与肺总量(TLC)呈正相关(r=0.91,P0.05)。呼气相全肺容积值(Vex)与残气量(Rv)呈正相关(r=0.79,P0.05)。结论 CT后处理技术在肺癌围手术期中的应用,对肺癌患者肺功能的评估提供新的可能,可以作为常规肺功能检查的补充。
[Abstract]:Objective to calculate the end-inspiratory and end-expiratory volume parameters of lung cancer patients by dual-source CT post-processing, and to evaluate the significance of the parameters compared with the traditional pulmonary function test (PFTs). Methods 32 patients with lung cancer were performed lung function examination and chest CT scan of deep inspiratory phase and deep expiratory chest within 1 week before operation. The lung volume at the end of inspiratory and end expiratory was obtained by SIEMENS workstation Volume and Pulmo module software. Ct postprocessing data were compared with the main data of pulmonary function examination, and correlation was analyzed by Pearson. Results preoperative inspiratory and expiratory lung volume differences (Vin-Vexx) were positively correlated with total lung volume (FEV1), forced vital capacity (FEV1) and forced vital capacity (FVC1) in patients with lung cancer. There was a positive correlation between TLC and TLC. There was a positive correlation between VX and RV in expiratory phase. Conclusion the application of CT post-processing technique in lung cancer perioperative period provides a new possibility for lung function evaluation in lung cancer patients and can be used as a supplement to routine lung function examination.
【作者单位】：北京大学国际医院胸外科;北京大学国际医院放射科;
【基金】：北京大学国际医院院内科研基金(No:YN2017QN07)
【分类号】：R730.44;R734.2

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