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乳腺叶状肿瘤与单纯型黏液癌的MRI征象及鉴别诊断

发布时间:2018-05-18 00:33

  本文选题:乳腺肿瘤 + 叶状肿瘤 ; 参考:《放射学实践》2017年02期


【摘要】:目的:探讨乳腺叶状肿瘤(PT)和单纯型黏液癌(PMBC)的MRI表现和鉴别诊断。方法:回顾性分析经手术病理证实的16例PT和23例PMBC的临床及MRI资料,包括发病年龄、MRI征象、Fischer评分结合BI-RADS分类、早期增强率(EER),对两者的上述资料进行统计学分析。结果:PT的发病年龄比PMBC小(t=-2.189,P0.05);PT和PMBC在T1及T2信号特征、内部强化特征、时间-信号强度曲线(TIC)类型上差异均具有统计学意义(P均0.05);PT和PMBC在病灶大小、形态、边缘、低信号分隔、邻近血管征象(AVS)、Fischer评分结合BI-RADS分类上均无统计学差异(P均0.05);PT的EER高于PMBC(P0.05),EER鉴别诊断PT和PMBC的受试者操作特征(ROC)曲线下面积为0.750,最佳界值为136.25%,诊断试验的敏感度为68.8%,特异度为81.8%,诊断符合率为76.3%。结论:虽然PT和PMBC的MRI表现多有重叠,但结合多个征象进行综合分析有助于两者的鉴别诊断。
[Abstract]:Objective: to investigate the MRI findings and differential diagnosis of phyllodes tumor (PTT) and simple mucinous carcinoma (PMBC). Methods: the clinical and MRI data of 16 cases of PT and 23 cases of PMBC confirmed by operation and pathology were analyzed retrospectively, including the age of onset and the grade of Fischer and the classification of BI-RADS. The early enhancement rate was analyzed statistically. Results there were statistically significant differences in T1 and T2 signal characteristics, internal enhancement characteristics, time-signal intensity curve (TICI) types between PT and PMBC in the age of onset than those in PMBC. There were significant differences between PT and PMBC in the size, shape, edge and low signal intensity of the lesions. There was no statistical difference between the BI-RADS classification and the Fischer score of adjacent vascular signs. The area under the curve of EER in the differential diagnosis of PT and PMBC was 0.750, the optimal threshold was 136.25, the sensitivity of diagnostic test was 68.8%, the area under the curve of differential diagnosis PT and PMBC was 0.750, and the sensitivity of diagnostic test was 68.8%. The heterogeneity was 81.8 and the diagnostic coincidence rate was 76.3. Conclusion: although the MRI findings of PT and PMBC are overlapped, comprehensive analysis of multiple signs is helpful for differential diagnosis of PT and PMBC.
【作者单位】: 中国医科大学肿瘤医院、辽宁省肿瘤医院医学影像科;
【分类号】:R737.9;R445.2

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