侵犯视神经管鞍区脑膜肿瘤术后视力影响因素分析

发布时间：2018-05-18 03:04

本文选题：视神经管 + 脑膜肿瘤　；参考：《中国神经精神疾病杂志》2017年09期

【摘要】：目的探讨改善侵犯视神经管的脑膜肿瘤术后视力水平的影响因素。方法收集侵犯视神经管的脑膜肿瘤患者的临床资料,logistic回归分析性别、年龄、肿瘤大小、术前视力、肿瘤切除程度、肿瘤粘连周围结构程度、视神经管减压时机和患者视力转归的关系。结果共55例,术后视力改善26例,无改善29例。早期硬膜外视神经管减压17例,视力好转15例;后期视神经管减压9例,视力好转5例;单纯刮除29例,视力好转6例。单因素分析提示切除级别、肿瘤粘连程度和早期硬膜外视神经管减压可影响术后视力改善;logistic回归分析显示早期硬膜外视神经管减压是改善术后视力的唯一保护因素。结论对于术前考虑已经侵犯视神经管的鞍区脑膜肿瘤,术中宜行早期硬膜外视神经管减压以改善患者术后视力。
[Abstract]:Objective to investigate the influencing factors on postoperative visual acuity of meningeal tumors invading optic canal. Methods the clinical data of patients with meningeal tumor invading optic canal were collected. Logistic regression analysis was performed on sex, age, tumor size, preoperative visual acuity, degree of tumor resection, degree of surrounding structure of tumor adhesion. The relationship between the time of optic canal decompression and the outcome of visual acuity. Results in 55 cases, the visual acuity was improved in 26 cases and no improvement in 29 cases. 17 cases had early decompression of epidural optic canal, 15 cases had improved visual acuity, 9 cases had decompression of optic canal and 5 cases had improved visual acuity, 29 cases had simple curettage, 6 cases had improved visual acuity. Univariate analysis showed that resection grade, degree of tumor adhesion and early decompression of epidural optic canal could affect postoperative visual acuity. Logistic regression analysis showed that early decompression of epidural optic canal was the only protective factor to improve postoperative visual acuity. Conclusion in order to improve the postoperative visual acuity of patients with Sellar meningiomas which have invaded optic canal before operation, early decompression of epidural optic canal should be performed during operation.
【作者单位】：佛山市第一人民医院神经外科;中山大学附属第一医院神经外科;
【基金】：佛山市自筹经费类科技计划项目(编号:2014AB00282)
【分类号】：R739.45

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