红花注射液对乳腺癌术后上肢淋巴水肿临床疗效的影响

发布时间：2018-05-28 03:19

本文选题：乳腺癌手术 + 上肢淋巴水肿　；参考：《辽宁中医药大学》2017年硕士论文

【摘要】：目的:将红花注射液应用于乳腺癌改良根治术后上肢淋巴水肿的患者,通过评价患者治疗前后的患侧上肢周径、水肿分级及临床疗效的改善情况,评价用红花注射液治疗乳腺癌改良根治术后上肢淋巴水肿患者的疗效,为今后临床上应用中医药治疗乳腺癌改良根治术后上肢淋巴水肿提供临床依据。材料与方法:选择2015年1月至2016年10月在辽宁省肿瘤医院接受乳腺癌改良根治手术后发生上肢水肿的患者49例,年龄在31至64周岁之间。按手术时间和随机数字表分为观察组(25例)和对照组(24例)。两组对象均接受我科乳腺癌术后上肢水肿常规治疗,包括低盐饮食、弹力绷带加压包扎的压迫疗法、压迫疗法下的上肢功能锻炼和患肢物理疗法等。观察组给予静脉滴注红花注射液,连续用药30天。将两组患者患侧上肢周径及水肿程度进行比较,从而评估红花注射液对乳腺癌改良根治术后上肢淋巴水肿的临床疗效。结果:1两组患者发病年龄、发生上肢水肿距乳腺癌改良根治术后时间及上肢水肿严重程度比较无统计学差异(P0.05)。2生物学指标比较:两组对象治疗前患肢上臂围、前臂围测试值分布接近(P0.05);治疗结束后,观察组患肢上臂围、前臂围测试值明显低于治疗前及对照组同期结果(P0.05)。3临床疗效指标比较:观察组中显效5例(20.00%)和有效16例(64.00%),总有效率84.00%,无效4例(16.00%),明显优于对照组。结论:1红花注射液能够缩小乳腺癌改良根治术后患侧上肢淋巴水肿的上肢周径,减轻水肿程度。2静脉滴注红花注射液的观察组明显优于对照组。3红花注射液治疗乳腺癌改良根治术后上肢淋巴水肿的疗效确切。
[Abstract]:Objective: to apply safflower injection to the patients with upper limb lymphedema after modified radical mastectomy. To evaluate the therapeutic effect of safflower injection on upper limb lymphedema after modified radical mastectomy, and to provide clinical basis for the treatment of upper limb lymphedema after modified radical mastectomy with traditional Chinese medicine. Materials and methods: 49 patients with upper limb edema after modified radical mastectomy were selected from January 2015 to October 2016 in Liaoning Cancer Hospital, aged between 31 and 64 years. According to the operation time and random number table, the observation group (n = 25) and the control group (n = 24) were divided into two groups. The two groups received routine treatment of upper limb edema after breast cancer operation, including low-salt diet, compression therapy with elastic bandage, upper limb function exercise and physical therapy of affected limbs, etc. In the observation group, safflower injection was given intravenously for 30 days. In order to evaluate the clinical effect of safflower injection on upper limb lymphedema after modified radical mastectomy, the peripheral diameter and edema degree of upper extremity were compared between the two groups. Results there was no significant difference in the age of onset, the time between the onset of upper limb edema and the time after modified radical mastectomy and the severity of upper limb edema between the two groups. The distribution of the forearm circumference was close to that of P0.05.After the treatment, the upper arm circumference of the affected limb was observed in the observation group. The value of forearm circumference test was significantly lower than that before treatment and the control group (P 0.053.Compared with the clinical curative effect index: in the observation group, 5 cases had remarkable effect (20. 00) and 16 cases were effective, the total effective rate was 84. 00 and 4 cases were ineffective, which was obviously superior to that of the control group. Conclusion 1 safflower injection can reduce the peripheral diameter of upper limb lymphedema in the affected side after modified radical mastectomy. The observation group was better than the control group in the treatment of upper limb lymphedema after modified radical mastectomy, and the observation group was superior to the control group in the treatment of upper limb lymphedema after modified radical mastectomy.
【学位授予单位】：辽宁中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R737.9

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