扶正平瘤汤联合替莫唑胺治疗脑胶质瘤术后的临床观察

发布时间：2018-05-31 15:02

本文选题：脑胶质瘤 + 扶正平瘤汤　；参考：《黑龙江中医药大学》2017年硕士论文

【摘要】：目的:使用扶正平瘤汤联合替莫唑胺治疗脑胶质瘤术后的患者,观察其临床疗效。方法:将符合入组标准的60例脑胶质瘤术后患者进行随机分组,分为治疗组和对照组。治疗组采用扶正平瘤汤联合替莫唑胺进行治疗,对照组采用替莫唑胺治疗。对两组患者治疗前后的肿瘤影像学疗效、生活质量评分、中医证候改善情况、毒副反应等进行观察统计,将所得的结果用SPSS17.0软件进行统计学处理。结果:(1)治疗照组在肿瘤影像学疗效的总有效率上高于对照组(P0.05)。(2)治疗组在改善病人生活质量上优于对照组(P0.05)。(3)治疗组在中医证候的改善情况上优于对照组(P0.05)。(4)治疗组毒副反应的发生率低于对照组(P0.05)。结论:应用扶正平瘤汤联合替莫唑胺对脑胶质瘤术后的患者进行同步治疗,能够改善患者临床症状、提高患者生存质量,延缓肿瘤的生长。
[Abstract]:Objective: to observe the clinical effect of Fuzheng Pingliu decoction combined with temozolidomide in the treatment of glioma after operation. Methods: 60 patients with glioma were randomly divided into treatment group and control group. The treatment group was treated with Fuzheng Pingliu decoction combined with temozolidomide, while the control group was treated with temozolidomide. Two groups of patients before and after treatment of tumor imaging efficacy, quality of life score, TCM syndromes improvement, toxic side effects were observed and statistics, the results obtained by SPSS17.0 software for statistical processing. Results: 1) the total effective rate of radiology in the treatment group was higher than that in the control group (P 0.05. 05) the treatment group was superior to the control group in improving the quality of life of the patients (P 0. 05. 0. 0. 3) the improvement of TCM syndromes in the treatment group was better than that in the control group (P 0. 05, P 0. 05, P 0. 05, P < 0. 05). The incidence of side effects was lower than that of control group (P 0.05). Conclusion: the application of Fuzheng Pingliu decoction and temozolidomide in the treatment of glioma patients after operation can improve the clinical symptoms, improve the quality of life of the patients, and delay the growth of the tumor.
【学位授予单位】：黑龙江中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R739.41

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