术后早期肠内营养在胃癌病人治疗中的临床观察

发布时间：2018-06-17 12:37

本文选题：胃癌 + 早期肠内营养　；参考：《肠外与肠内营养》2017年04期

【摘要】：目的:运用快速康复理论,通过比较早期肠内营养(EEN)和常规肠内营养(EN)组间围手术期病人营养状况、炎症指标、免疫水平及临床指标,观察EEN对胃癌病人术后恢复的影响。方法:前瞻性分析65例胃癌术后病人,按照不同时间EN支持分为EEN组(n=33)和EN组(n=32)。比较两组病人术前1天、术后第3天和术后第7天的血清总蛋白、血清白蛋白、前白蛋白、白细胞总数、C反应蛋白以及T淋巴细胞亚群、免疫球蛋白(Ig G),同时观察病人早期胃肠道恢复时间、住院天数及平均住院费用等指标。结果:EEN组病人术后第7天营养指标和细胞免疫指标大多高于EN组,EEN组病人术后第3天炎症指标低于EN组,两组间有显著差异(P0.05)。EEN组在术后短期内免疫水平和临床恢复及住院时间方面都优于EN组(P0.05)。结论:胃癌术后早期肠内营养支持,对早期提高术后病人营养状况、免疫功能及减轻炎症反应具有显著作用,促进了胃肠功能的恢复,缩短了住院时间。
[Abstract]:Objective: to observe the effect of EEN on postoperative recovery of gastric cancer patients by comparing the nutritional status, inflammatory index, immune level and clinical index between early enteral nutrition (EEN) group and routine enteral nutrition (en) group by using the theory of rapid rehabilitation. Methods: 65 patients with gastric cancer after operation were prospectively analyzed and divided into two groups according to the different time of en support: EEN group (n = 33) and en group (n = 32). Serum total protein, serum albumin, prealbumin, total leukocyte count C reactive protein and T lymphocyte subsets were compared between the two groups 1 day before operation, 3 days after operation and 7 days after operation. The time of early gastrointestinal recovery, the days of hospitalization and the average cost of hospitalization were also observed. Results on the 7th day after operation, the nutritional and cellular immune indexes of the patients in the% EEN group were significantly higher than those in the en group on the third day after operation, and were lower than those in the en group on the third day after operation. There was a significant difference between the two groups in the immune level, clinical recovery and hospital stay in the short term after operation, which was better than that in the en group (P 0.05). Conclusion: early enteral nutrition support plays a significant role in improving the nutritional status, immune function and reducing inflammatory reaction of postoperative patients, promoting the recovery of gastrointestinal function and shortening the hospitalization time.
【作者单位】：赣南医学院第一附属医院胃肠外科;
【分类号】：R459.3;R735.2

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