功能区脑膜瘤术后发生肢体肌力下降的危险因素分析

发布时间：2018-07-15 15:41

【摘要】：目的:探讨手术切除功能区脑膜瘤后发生肢体肌力下降的相关危险因素。方法:对2012年2月至2016年5月在广西医科大学第一附属医院神经外科,经过手术切除治疗的62例功能区脑膜瘤患者的临床资料进行回顾性分析,根据肌力评分标准,分为肌力下降组和非肌力下降组,进行单因素及多因素Logistic回归分析两组病人的性别、年龄、肿瘤大小、术前瘤周水肿、术前癫痫发作、术后癫痫发作、手术时间、出血量、是否二次手术、糖尿病、高血压、是否在窦旁、术后是否并发颅内感染等因素。结果:单因素分析显示年龄(X2=5.641,P=0.018)、肿瘤大小(X2=4.986,P=0.028)、手术时间(X2=3.994,P=0.045)、性别(X2=0.316,P=0.384)、术前瘤周水肿(X2=0.056,P=0.23)、术前癫痫(X2=0.261,P=0.411)、术后癫痫(X2=1.130,P=0.254)、出血量(X2=1.159,P=0.217)、是否二次手术(X2=0.642,P=0.613)、糖尿病(X2=1.039,P=0.289)、高血压(X2=0.384,P=0.378)、是否在窦旁(X2=0.079,P=0.499)、是否颅内感染(X2=0.038,P=0.669)。比较这些因素的差异是否有统计学意义。Logistic回归分析以上因素显示出年龄≥60岁(OR=4.017,P=0.023)、肿瘤≥4cm(OR=4.335,P=0.032),为功能区脑膜瘤术后出现肌力下降的相关因素。结论:年龄≥60岁及肿瘤≥4cm是术后发生肢体肌力下降的危险因素。
[Abstract]:Objective: to investigate the risk factors of limb myoplegia after resection of meningioma in functional area. Methods: from February 2012 to May 2016, 62 patients with meningioma in the functional area were treated by surgical resection in the Neurosurgery Department of the first affiliated Hospital of Guangxi Medical University. The clinical data of 62 patients with meningioma in the functional area were analyzed retrospectively according to the criteria of muscle strength score. The patients were divided into two groups: dyskinesia group and non-dyskinetic group. The sex, age, tumor size, peri-tumor edema, epileptic seizure before operation, seizure after operation, operation time, bleeding volume were analyzed by univariate and multivariate logistic regression analysis. Whether secondary surgery, diabetes, hypertension, whether in the sinus, postoperative intracranial infection and other factors. 缁撴灉:鍗曞洜绱犲垎鏋愭樉绀哄勾榫，

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