胃癌术后肺部并发症相关危险因素分析
发布时间：2018-07-27 12:46
【摘要】：目的比较胃癌术后发生肺部并发症病人与无并发症病人间临床病理特征,并分析胃癌术后肺部并发症发生的危险因素。方法回顾性分析2012年1月至2015年12月四川大学华西医院胃肠外科收治的719例胃癌手术病人临床资料。排除残胃癌、术前接受化疗以及无肺部并发症但合并其他并发症病例后,分为肺部并发症组(103例)与无并发症组(616例)。结果肺部并发症组病人术后住院时间较无并发症组延长[(13.5±7.0)d vs.(10.7±3.1)d,P0.001],其余指标组间差异无统计学意义(P0.05)。单因素分析显示,年龄(P=0.018)、肺部疾病史(P0.001)、术前肺功能[1 s用力呼气量与用力肺活量比值(FEV1/FVC),P=0.002]、血红蛋白(P=0.004)、术中出血(P=0.042)以及手术时间(P=0.048)与肺部并发症发生相关;多因素分析发现,肺部疾病史(P0.001)、术前肺功能(P=0.032)以及血红蛋白(P=0.004)为影响胃癌术后肺部并发症发生的独立危险因素。结论对于BMI≥25、合并肺部基础疾病、FEV1/FVC60、血红蛋白90 g/L的胃癌病人,应注意采取必要措施以减少术后肺部并发症发生。
[Abstract]:Objective to compare the clinicopathological features of lung complications after gastric cancer operation and to analyze the risk factors of lung complications after gastric cancer surgery. Methods from January 2012 to December 2015, 719 patients with gastric cancer underwent gastrointestinal surgery in Huaxi Hospital of Sichuan University were retrospectively analyzed. After exclusion of gastric stump gastric cancer, chemotherapy before operation and without pulmonary complications but complicated with other complications, the patients were divided into pulmonary complication group (n = 103) and non-complication group (n = 616). Results the postoperative hospitalization time of pulmonary complication group was longer than that of no complication group [(13.5 卤7.0) d vs. (10.7 卤3.1) dP0.001], and there was no significant difference between other groups (P0.05). Univariate analysis showed that age (P0. 018), history of pulmonary disease (P0. 001), preoperative pulmonary function [1 s forced expiratory volume to forced vital capacity (FEV1/FVC) / P0. 002], hemoglobin (P0. 004), intraoperative hemorrhage (P0. 042) and operative time (P0. 048) were associated with pulmonary complications. Pulmonary disease history (P0.001), preoperative pulmonary function (P0. 032) and hemoglobin (P0. 004) were independent risk factors for pulmonary complications after gastric cancer surgery. Conclusion for gastric cancer patients with BMI 鈮，
本文编号：2147878
[Abstract]:Objective to compare the clinicopathological features of lung complications after gastric cancer operation and to analyze the risk factors of lung complications after gastric cancer surgery. Methods from January 2012 to December 2015, 719 patients with gastric cancer underwent gastrointestinal surgery in Huaxi Hospital of Sichuan University were retrospectively analyzed. After exclusion of gastric stump gastric cancer, chemotherapy before operation and without pulmonary complications but complicated with other complications, the patients were divided into pulmonary complication group (n = 103) and non-complication group (n = 616). Results the postoperative hospitalization time of pulmonary complication group was longer than that of no complication group [(13.5 卤7.0) d vs. (10.7 卤3.1) dP0.001], and there was no significant difference between other groups (P0.05). Univariate analysis showed that age (P0. 018), history of pulmonary disease (P0. 001), preoperative pulmonary function [1 s forced expiratory volume to forced vital capacity (FEV1/FVC) / P0. 002], hemoglobin (P0. 004), intraoperative hemorrhage (P0. 042) and operative time (P0. 048) were associated with pulmonary complications. Pulmonary disease history (P0.001), preoperative pulmonary function (P0. 032) and hemoglobin (P0. 004) were independent risk factors for pulmonary complications after gastric cancer surgery. Conclusion for gastric cancer patients with BMI 鈮，
本文编号：2147878
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