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腹腔镜和开腹手术治疗中国老年宫颈癌疗效的Meta分析

发布时间:2018-07-27 16:38
【摘要】:目的比较腹腔镜与开腹手术治疗中国老年宫颈癌的疗效。方法计算机检索中国生物医学文摘数据库(CBM)、万方全文数据库(wanfangdata)、中国知网全文数据库(CNKI)、维普中文期刊数据库(VIP)和Pub Med,根据入选标准筛选文献。从文献提取数据,采用Rev Man 5.2.9软件进行统计学分析。结果最终纳入符合标准的文献10篇,均为临床对照研究(CCT),无随机对照研究(RCT)。腹腔镜手术组与开腹手术组患者年龄、体重、肿瘤分期等基本特征无明显差异。与开腹手术相比,腹腔镜手术组手术时间长(MD=32.60,95%CI:5.65~59.55,P=0.020),术中失血量少(MD=-94.01,95%CI:-130.65~-57.37,P=0.000),清除淋巴结数量少(MD=1.69,95%CI:0.67~2.72,P=0.001),术后排气时间早(MD=-17.09,95%CI:-21.19~-12.98,P=0.000),住院时间短(MD=-4.30,95%CI:-5.57~-3.02,P=0.000),差异有统计学意义。而术后留置尿管时间(MD=-0.67,95%CI:-1.92~0.58,P=0.290)、手术并发症发生率(OR^=0.62,95%CI:0.27~1.42,P=0.260),差异无统计学意义。结论腹腔镜手术具有创伤小、恢复快等优势,并不增加手术并发症发生率,是治疗中国老年宫颈癌的理想术式。
[Abstract]:Objective to compare the efficacy of laparoscopy and laparotomy in the treatment of elderly cervical cancer in China. Methods the Chinese biomedical abstract database (CBM), Wanfang full-text database (wanfangdata), (CNKI), Weipu Chinese periodical database (VIP) and Pub Medwere searched by computer and the literature was screened according to the selected criteria. The data were extracted from the literature and analyzed statistically by Rev Man 5.2.9 software. Results Ten articles were included in the standard, all of which were clinical controlled study, (CCT), no randomized controlled study, (RCT). There was no significant difference in age, weight and tumor stage between laparoscopy group and open operation group. 涓庡紑鑵规墜鏈浉姣,

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